85240-04-6

Upstream product

• 15074-54-1 2-chlorophenyl dichlorophosphate 
• 50-89-5 thymidine 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 76958-58-2 [1,2,4]Triazol-1-yl-phosphonic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 
• 80817-40-9 2'-deoxythymidine-3'-O-(2-chlorophenyl-2-cyanoethyl)phosphate 
• 72351-28-1 2-chlorophenyl phosphordi(1H-1-[1,2,4]triazolide) 
• 80817-37-4 5'-O-(dimethoxytrityl)thymidine 3'-(o-chlorophenyl β-cyanoethyl phosphate) 
• 81196-20-5 2-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl phosphate 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 75251-83-1 5'-O-dimethoxytritylthymidylyl-(3',5')-(o-chlorophenyl)-thymidylyl-3'-β-cyanoethyl(o-chlorophenyl)phosphate 

Downstream Products

• 90335-76-5 C₇₂H₇₁Cl₃N₇O₂₄P₃ 

Relevant academic research and scientific papers

Efficient and flexible access to fully protected trinucleotides suitable for DNA synthesis by automated phosphoramidite chemistry

An efficient synthetic approach to protected trinucleotide phosphoramidites suitable for codon-by-codon synthesis of structural gene combinatorial libraries is described; the procedure rests on the use of a pair of orthogonal protecting groups for the two

53. Nucleoside und Nucleotide. Teil 22. Synthese eines Tridecanucleosiddodecaphosphats, das die unnatuerliche Base 2(1H)-Pyrimidinon enthaelt

Nucleosides and Nucleotides.Part 22.Synthesis of a Tridecanucleoside Dodecaphosphate Containing the Unnatural Base 2(1H)-Pyrimidinone.The tridecanucleosid dodecaphosphate d(TpTpMpCpCpTpCpApApApApTpC) incorporating the modified nucleoside 1-(2'-deoxy-β-D-r

Simplified Liquid-Phase Preparation of Four Decadeoxyribonucleotides and their Preliminary Spectroscopic Characterization

Four self-complementary decadeoxyribonucleotides, dApTpApTpApTpApTpApT,dApTpApTpCpGpApTpApT, dApTpApTpGpCpApTpApT and dApApApApApTpTpTpTpT, were chemically synthesized by the phosphotriester procedure.Efforts were concentrated on keeping the procedure as simple as possible, concomitant with obtaining high-purity products at each step of the process.The decamers were elaborated from the 3'-end, starting with a 3'-O-benzoylated monomer according to the scheme: monomer + monomer -> dimer + dimer -> tetramer + dimer -> hexamer + tetramer -> decamer.Putity of intermediates and of the fully blocked decamers were monitored by chromatography and by 300-MHz 1H-NMR. spectroscopy.The deblocked decadeoxyribonucleotides were characterized by their UV., CD., and 1H-NMR. spectra.