852449-75-3Relevant academic research and scientific papers
Expanding the Scope of the Gold(I)-Catalyzed Rautenstrauch Rearrangement: Protic Additives
Bürki, Cédric,Whyte, Andrew,Arndt, Sebastian,Hashmi, A. Stephen K.,Lautens, Mark
, p. 5058 - 5061 (2016/10/14)
The synthesis of substituted 2-cyclopentenones using a commercially available gold(I) catalyst is described under flexible reaction conditions. During the course of our investigations, we discovered that using a proton source as an additive is required to obtain the desired substituted cyclopentenones in good yields.
Rh-Catalyzed [5+1] and [4+1] cycloaddition reactions of 1,4-enyne esters with co: A shortcut to functionalized resorcinols and cyclopentenones
Fukuyama, Takahide,Ohta, Yuko,Brancour, Celia,Miyagawa, Kazusa,Ryu, Ilhyong,Dhimane, Anne-Lise,Fensterbank, Louis,Malacria, Max
, p. 7243 - 7247 (2012/07/03)
We have developed novel Rh-catalyzed [n+1]-type cycloadditions of 1,4-enyne esters, which involve an acyloxy migration as a key step. The efficient preparation of functionalized resorcinols, including biaryl derivatives, from readily available 1,4-enyne esters and CO was achieved by Rh-catalyzed [5+1] cycloaddition accompanied by 1,2-acyloxy migration. When enyne esters had an internal alkyne moiety, the reaction proceeded by a [4+1]-type cycloaddition involving 1,3-acyloxy migration, leading to cyclopentenones.
Synthesis of functionalized resorcinols by rhodium-catalyzed [5+1] cycloaddition reaction of 3-acyloxy-1,4-enynes with CO
Brancour, Celia,Fukuyama, Takahide,Ohta, Yuko,Ryu, Ilhyong,Dhimane, Anne-Lise,Fensterbank, Louis,Malacria, Max
supporting information; experimental part, p. 5470 - 5472 (2010/09/18)
A novel [5+1] type carbonylative cycloaddition reaction has been developed using a Rh complex as catalyst. This reaction can convert readily available 3-acyloxy-1,4-enynes and CO to a wide range of functionalized resorcinols in good yields. A mechanism involving Rh-catalyzed cyclocarbonylation of 3-acyloxy-1,4-enynes accompanied by a 1,2-acyloxy shift is proposed for the present [5+1] type cycloaddition reaction. The Royal Society of Chemistry 2010.
