852459-72-4Relevant academic research and scientific papers
Synthesis of PI-88 analogue using novel O-glycosidation of exo-methylenesugars
Namme, Rie,Mitsugi, Takashi,Takahashi, Hideyo,Ikegami, Shiro
, p. 3033 - 3036 (2007/10/03)
Acid-promoted α-stereoselective O-glycosidation of 1-exo-methylenesugars was successfully applied to the synthesis of a PI-88 analogue. By using methanesulfonic acid as a promoter, 1′-C-methyl- α-disaccharides with p-methoxybenzyl protection were obtained in high yield. The sequence of selective deprotection and glycosidation provided 1-C-methyl-pentasaccharide efficiently.
