852546-84-0

Basic information

• Product Name: (2S,3aS,6aS)-benzyl octahydrocyclopenta[b]pyrrole-2-carboxylate 4-toluenesulfonate (1:1)
• Synonyms: (2S,3aS,6aS)-benzyl octahydrocyclopenta[b]pyrrole-2-carboxylate 4-toluenesulfonate (1:1)
• CAS NO: 852546-84-0
• Molecular Weight: 417.526
• Mol File: 852546-84-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2S,3aS,6aS)-benzyl octahydrocyclopenta[b]pyrrole-2-carboxylate 4-toluenesulfonate (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3aS,6aS)-benzyl octahydrocyclopenta[b]pyrrole-2-carboxylate 4-toluenesulfonate (1:1)(852546-84-0)
• EPA Substance Registry System: (2S,3aS,6aS)-benzyl octahydrocyclopenta[b]pyrrole-2-carboxylate 4-toluenesulfonate (1:1)(852546-84-0)

Safety Data

• Hazardous Substances Data: 852546-84-0(Hazardous Substances Data)

Upstream product

• 411232-21-8 (2S)-octahydrocyclopenta[b]pyrrole-2-carboxylic acid 
• 104-15-4 toluene-4-sulfonic acid 
• 100-51-6 benzyl alcohol 
• 109428-53-7 (2S,3aS,6aS)-1-(tert-butoxycarbonyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid 

Downstream Products

• 87269-88-3 2--L-alanyl>-(1S,3S,5S)-2-azabicyclo<3.3.0>octane-3-carboxylic acid benzylester 

Relevant articles and documents

METHOD FOR THE SYNTHESIS OF A RAMIPRIL INTERMEDIATE

The present invention relates to a process for the preparation of octahydrocyclopenta[b]pyrrole-2-carboxylic acid and esters thereof of general formula (1) in the presence of a cobalt and/or nickel comprising catalyst and to the use of compounds of general formula (1) in the synthesis of ramipril.

NOVEL CARBAMOYLGLYCINE DERIVATIVES

The present invention relates to carbamoylglycine derivatives, a process for the preparation of carbamoylglycine derivatives and the use of carbamoylglycine derivatives in the preparation of enantiomerically enriched α-amino acids. Furthermore, the present invention relates to the preparation of pharmaceutically active products such as perindopril and ramipril using the novel carbamoylglycine derivatives.

A PROCESS FOR INDUSTRIALLY VIABLE PREPARATION OF (S,S,S) PHENYLMETHYL-2-AZABICYCLO-[3.3.0]-OCTANE-3-CARBOXYLATE TOSYLATE

A process for industrially viable preparation of a hitherto unreported intermediate viz., [s, s, s] phenylmethyl -2-azabicyclo [3.3.0]-octane-3-carboxylae tosylate by reacting methyl-N-acetyl- R-chloro alaninate of formula-II with 1-(1-pyrrolidinyl)-cyclo