852568-11-7Relevant academic research and scientific papers
Efficient polymer-assisted strategy for the deprotection of protected oligosaccharides
Tanaka, Hiroshi,Ishida, Tadasuke,Matoba, Nobuatsu,Tsukamoto, Hirokazu,Yamada, Haruo,Takahashi, Takashi
, p. 6349 - 6352 (2007/10/03)
(Chemical Equation Presented) New strategies in sugar synthesis: A prelinker containing a dihydropyranyl moiety and an activated ester can be attached to a sugar, which is then loaded onto an amino-modified support by amidation. Standard protecting-group manipulations are possible. Final cleavage of the linker under mildly acidic conditions provides the fully deprotected oligosaccharides. TFA=trifluoroacetic acid.
Automated parallel synthesis of a protected oligosaccharride library based upon the structure of dimeric Lewis X by one-pot sequential glycosylation
Tanaka, Hiroshi,Matoba, Nobuatsu,Tsukamoto, Hirokazu,Takimoto, Hisami,Yamada, Haruo,Takahashi, Takashi
, p. 824 - 828 (2007/10/03)
An efficient synthesis of a protected dimeric Lewis X epitope by two sequential one-pot glycosylations is described. Combinatorial synthesis of the dimeric Lewis X epitope derivatives by the one-pot glycosylation was accomplished utilizing an automated synthesizer to provide 12-protected oligosaccharides.
