85260-52-2Relevant academic research and scientific papers
SYNTHETIC CONTROL LEADING TO CHIRAL COMPOUNDS
Mukaiyama, Teruaki,Iwasawa, Nobuharu,Stevens, Rodney W.,Haga, Toru
, p. 1381 - 1390 (2007/10/02)
A highly diastereoselective cross aldol reaction is developed using divalent tin enolates formed from stannous trifluoromethanesulfonate and carbonyl compounds.The reaction is extended to a highly enantioselective cross aldol reaction employing chiral dia
HIGHLY ENANTIOSELECTIVE ALDOL-TYPE REACTION OF 3-ACETYLTHIAZOLIDINE-2-THIONE WITH ACHIRAL ALDEHYDES
Iwasawa, Nobuharu,Mukaiyama, Teruaki
, p. 297 - 298 (2007/10/02)
A highly enantioselective aldol-type reaction forming various β-hydroxy carbonyl compounds from 3-acetylthiazolidine-2-thione and achiral aldehydes is achieved via divalent tin enolate employing chiral diamine derived from (S)-proline as a ligand.
STANNOUS TRIFLATE MEDIATED ALDOL REACTION OF 3-ACYLTHIAZOLIDINE-2-THIONE: A CONVENIENT METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF β-HYDROXY ALDEHYDE AND β-HYDROXY CARBOXYLIC ACID DERIVATIVES
Mukaiyama, Teruaki,Iwasawa, Nobuharu
, p. 1903 - 1906 (2007/10/02)
Divalent tin enolates, formed from stannous triflate and 3-acylthiazolidine-2-thiones, react with aldehydes with erythro-selectivities.The adducts are easily transformed into β-hydroxy aldehyde and β-hydroxy carboxylic acid derivatives.
