852603-86-2 Usage
Uses
Used in Organic Synthesis:
trans-4-phenyl-1-but-1-enylboronic acid is used as a synthetic intermediate for the preparation of various organic compounds. Its unique structure allows it to participate in a range of reactions, such as cross-coupling and Suzuki-Miyaura reactions, which are essential for the synthesis of complex organic molecules.
Used in Fluorination Reactions:
trans-4-phenyl-1-but-1-enylboronic acid is used as a precursor for the preparation of alkenyltrifluoroborates through fluorination reactions. This application is particularly important in the synthesis of fluorinated organic compounds, which have a wide range of applications in pharmaceuticals, agrochemicals, and materials science due to the unique properties conferred by fluorine atoms.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, trans-4-phenyl-1-but-1-enylboronic acid is used as a building block for the development of new drugs. Its ability to participate in various synthetic pathways makes it a valuable component in the design and synthesis of novel pharmaceutical agents with potential therapeutic applications.
Used in Materials Science:
In materials science, trans-4-phenyl-1-but-1-enylboronic acid is used as a component in the synthesis of advanced materials with specific properties. Its involvement in the formation of polymers, coatings, and other materials can lead to the development of new products with improved performance characteristics.
Overall, trans-4-phenyl-1-but-1-enylboronic acid is a versatile compound with a wide range of applications in various industries, including organic synthesis, pharmaceuticals, and materials science. Its unique structure and reactivity make it an important player in the development of new compounds and materials with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 852603-86-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,2,6,0 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 852603-86:
(8*8)+(7*5)+(6*2)+(5*6)+(4*0)+(3*3)+(2*8)+(1*6)=172
172 % 10 = 2
So 852603-86-2 is a valid CAS Registry Number.
852603-86-2Relevant academic research and scientific papers
Efficient hydrolysis of organotrifluoroborates via silica gel and water
Molander, Gary A.,Cavalcanti, Livia N.,Canturk, Belgin,Pan, Po-Shen,Kennedy, Lauren E.
supporting information; experimental part, p. 7364 - 7369 (2010/01/16)
(Chemical Equation Presented) A general, mild, and efficient method for the hydrolysis of organotrifluoroborates to unveil boronic acids using silica gel and H2O was developed. This method proved to be tolerant of a broad range of aryl-, heteroaryl-, alkenyl-, and alkyltrifluoroborates as well as structurally diverse aminomethylated organotrifluoroborates.As anticipated, electron-rich substrates provided the corresponding boronic acids more readily than electron-poor substrates, owing to the resonance-stabilized difluoroborane intermediate. The method developed was expanded further for the conversion of organotrifluoroborates to the corresponding boronate esters. 2009 American Chemical Society.
Synthesis and biological evaluation of 6,7-disubstituted 4-aminopyrido[2,3-d]pyrimidines as adenosine kinase inhibitors
Perner, Richard J.,Lee, Chih-Hung,Jiang, Meiqun,Gu, Yu-Gui,DiDomenico, Stanley,Bayburt, Erol K.,Alexander, Karen M.,Kohlhaas, Kathy L.,Jarvis, Michael F.,Kowaluk, Elizabeth L.,Bhagwat, Shripad S.
, p. 2803 - 2807 (2007/10/03)
The synthesis and structure-activity relationship of a series of 6,7-disubstituted 4-aminopyrido[2,3-d]pyrimidines as novel non-nucleoside adenosine kinase inhibitors is described. A variety of substituents, primarily aryl, at the C6 and C7 positions of the pyridopyrimidine core were found to yield analogues that are potent inhibitors of adenosine kinase. In contrast to the 5,7-disubstituted and 5,6,7-trisubstituted pyridopyrimidine series, these analogues exhibited only modest potency to inhibit AK in intact cells.
