852632-55-4Relevant academic research and scientific papers
Difluorocarbene chemistry: Synthesis of gem-difluorocyclopropenylalkynes and 3,3,3′,3′-tetrafluorobicyclopropyl-1,1′-dienes
Cheng, Zhan-Ling,Chen, Qing-Yun
, p. 93 - 97 (2005)
A series of gem-difluorocyclopropenylalkynes are easily obtained in good yields by the Sonogashira reaction of 3,3-difluoro-1-iodocyclopropenes with terminal alkynes. Onto these new alkynes addition of difluorocarbene, generated from the decomposition of
Preparation and 13C NMR study on 1-aryl-3,3-difluoro-2-(phenylethynyl)cyclopropenes: long distance Hammett substituent effect
Lin, Shaw-Tao,Lee, Chuan-Chen,Wu, En-Chien
, p. 5103 - 5106 (2008/09/21)
Coupling of 1-aryl-3,3-difluoro-2-chlorocyclopropenes and phenylacetylene using Sonogashira reaction with Pd(OAc)2 and CuI as the catalyst with K2CO3 as a base yields phenylethynylcyclopropenes in high selectivity and good yields. The 13C chemical shifts of Cε of ～105 ppm on acetylene group significantly different from phenylacetylene (84 ppm) suggest that the acetylene group possesses less sp hybrid character due to an unusual long distance Hammett substituent effect. It is also confirmed by the substituent parameter analysis, while the Cβ and Cε display the strong resonance effect (their values are 6.89 and 3.37, respectively).
Difluorocarbene chemistry: Synthesis of gem-difluorocyclopropenylalkynes and 3,3,3′,3′-tetrafluorobicyclopropyl-1,1′-dienes
Cheng, Zhan-Ling,Chen, Qing-Yun
, p. 39 - 43 (2007/10/03)
A series of gem-difluorocyclopropenylalkynes are easily obtained in good yields by the Sonogashira reaction of 3,3-difluoro-1-iodocyclopropenes with terminal alkynes. Onto these new alkynes addition of difluorocarbene, generated from the decomposition of
