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4-(tert-butyl-dimethyl-silanyloxy)-2-(4-trifluoromethyl-benzyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 852633-21-7 Structure
  • Basic information

    1. Product Name: 4-(tert-butyl-dimethyl-silanyloxy)-2-(4-trifluoromethyl-benzyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
    2. Synonyms: 4-(tert-butyl-dimethyl-silanyloxy)-2-(4-trifluoromethyl-benzyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
    3. CAS NO:852633-21-7
    4. Molecular Formula:
    5. Molecular Weight: 517.661
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 852633-21-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(tert-butyl-dimethyl-silanyloxy)-2-(4-trifluoromethyl-benzyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(tert-butyl-dimethyl-silanyloxy)-2-(4-trifluoromethyl-benzyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester(852633-21-7)
    11. EPA Substance Registry System: 4-(tert-butyl-dimethyl-silanyloxy)-2-(4-trifluoromethyl-benzyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester(852633-21-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 852633-21-7(Hazardous Substances Data)

852633-21-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 852633-21-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,2,6,3 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 852633-21:
(8*8)+(7*5)+(6*2)+(5*6)+(4*3)+(3*3)+(2*2)+(1*1)=167
167 % 10 = 7
So 852633-21-7 is a valid CAS Registry Number.

852633-21-7Relevant articles and documents

Synthesis of 2,2-disubstituted pyrrolidine-4-carboxylic acid derivatives and their incorporation into β-peptide oligomers

Huck, Bayard R.,Gellman, Samuel H.

, p. 3353 - 3362 (2007/10/03)

(Chemical Equation Presented) We have recently shown that members of a new class of β-peptides, containing 2,2-disubstituted pyrrolidine-4-carboxylic acid residues, display discrete conformational preferences despite the impossibility of internal hydrogen bonding (Huck et al. J. Am. Chem. Soc. 2003, 125, 9035). Here we describe the synthesis of a variety of 2,2-disubstituted pyrrolidine-4-carboxylic derivatives that bear a diverse set of side chains and protecting groups suitable for oligomer synthesis. In addition, we discuss coupling methods for construction of oligomers in solution and on solid phase. Non-hydrogen bonded foldamers such as those generated from 2,2-disubstituted pyrrolidine-4-carboxylic acids may be useful in biomedical applications because the low intrinsic polarity of their backbones may promote bioavailability.

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