852676-79-0Relevant academic research and scientific papers
Lipase-catalyzed esterification of a (±)-2,3-di(arylmethyl)-1,4- butanediol and its application to the synthesis of (S,S)-(+)-hinokinin
Morimoto, Toshiaki,Nagai, Hazuki,Achiwa, Kazuo
, p. 857 - 865 (2005)
Racemic trans-2,3-di[(3,4-methylenedioxy)benzyl]-1,4-butanediol (dihydrocubebin) 6 was enantioselectively esterified using lipases as catalysts with vinyl acetate. Optically active (S,S)-1,4-butanediol 6 obtained was selectively oxygenated with a Fetizon reagent, affording (S,S)-(+)-hinokinin 9 in a high yield.
