85268-21-9Relevant academic research and scientific papers
Aggregative activation in heterocyclic chemistry. Part 4. Metallation of 2-methoxypyridine: Unusual behaviour of the new unimetal superbase BuLi-Me2N(CH2)2OLi (BuLi-LiDMAE)
Gros, Philippe,Fort, Yves,Caubere, Paul
, p. 3071 - 3080 (2007/10/03)
A series of potential unimetal superbases BuLi-ROLi has been studied in order to increase the basicity/ nucleophilicity ratio ([B/N]R) of BuLi. The best [B/N]R ratio is found with BuLi-LiDMAE. This complex base apparently metallates 2-methoxypyridine at t
Highly Regioselective Allylation of α-Enones and Epoxides with Lithium Tetraallyllanthanoid Ate Complex
Fukuzawa, Shin-ichi,Sakai, Shizuyoshi
, p. 3308 - 3314 (2007/10/02)
Tetraallyllanthanoid ate complex (1), which was readily prepared in situ from tetraallyltin, lanthanoid trichloride, and butyllithium in tetrahydrofuran (THF), reacts smoothly with α-enones (3-11) with a high degree of 1,2-regioselectivity (1,2:1,4 = >99:
Reactions of Carbonyl Compounds with Grignard Reagents in the Presence of Cerium Chloride
Imamoto, Tsuneo,Takiyama, Noboyuki,Nakamura, Kimikazu,Hatajima, Toshihiko,Kamiya, Yasuo
, p. 4392 - 4398 (2007/10/02)
The addition of Grignard reagents to ketones is significantly enhanced by cerium chloride with remarkable supression of side reactions, particularly enolization.Some esters, which are prone to side reactions, also react readily with Grignard reagents in the presence of cerium chloride to give normal reaction products in reasonable to high yields.
