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1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-5-bromo-1,3-dihydroisobenzofuran benzoate salt is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

852705-11-4

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852705-11-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 852705-11-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,2,7,0 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 852705-11:
(8*8)+(7*5)+(6*2)+(5*7)+(4*0)+(3*5)+(2*1)+(1*1)=164
164 % 10 = 4
So 852705-11-4 is a valid CAS Registry Number.

852705-11-4Downstream Products

852705-11-4Relevant academic research and scientific papers

A PROCESS FOR THE PREPARATION OF HIGH PURITY ESCITALOPRAM

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Page/Page column 14-15, (2008/06/13)

The present invention discloses an improved process for the preparation of high purity escitalopram base of formula (I) by reacting the acid addition salt of formula (XVIII) with copper (I) cyanide and with or without copper (I) iodide in dimethylformamide medium at 145-150 °C. Cyanation on the acid addition salt of formula (XVIII) is found to be superior in yield and quality over the parent base compound of formula (XVII). The process is compatible to scale up operations thereby making the process commercially viable for escitalopram oxalate. Escitalopram oxalate is an antidepressant available in the market.

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