85276-94-4

Basic information

• Product Name: 1,2,4-Triazine-3,5(2H,4H)-dione, 2-amino-4-methyl-6-phenyl-
• CAS NO: 85276-94-4
• Molecular Formula: C10H10N4O2
• Molecular Weight: 218.215
• Mol File: 85276-94-4.mol

Chemical Properties

• CAS DataBase Reference: 1,2,4-Triazine-3,5(2H,4H)-dione, 2-amino-4-methyl-6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Triazine-3,5(2H,4H)-dione, 2-amino-4-methyl-6-phenyl-(85276-94-4)
• EPA Substance Registry System: 1,2,4-Triazine-3,5(2H,4H)-dione, 2-amino-4-methyl-6-phenyl-(85276-94-4)

Safety Data

• Hazardous Substances Data: 85276-94-4(Hazardous Substances Data)

Upstream product

• 1566-37-6 3-methylmercapto-5-oxo-6-phenyl-2,5-dihydro-1,2,4-triazine 
• 37526-30-0 4-methyl-6-phenyl-1,2,4-triazine-3,5(2H,4H)-dione 
• 186581-53-3 diazomethane 
• 85276-93-3 2-amino-6-phenyl-1,2,4-triazine-3,5(2H,4H)-dione 

Relevant articles and documents

1,2,4-Triazines. 7. Regioselective N2-Amination of 3-Methylthio-1,2,4-triazin-5(2H)-ones. A Novel Synthesis of Triazolotriazinones and -triazine

A regioselective synthesis of 2-aminotriazinones 6a-d is reported, by reaction of 3-methylthio-1,2,4-triazinones 5a-d with O-(2,4-dinitrophenyl)hydroxylamine (2) as an amino-transfer agent.A spectroscopic study and an unequivocal synthesis of 2-amino-4-methyl-6-phenyl-1,2,4-triazinedione (11a) has shown the site of amination to be N2 of the 1,2,4-triazinone ring.Subsequent reaction of 2-amino-1,2,4-triazinones 6a-b with amines, followed by ring closure with aliphatic acids provided triazolotriazine-7(1H)-ones 13a-e.Conversion of triazolotriazinone 13c to unsubstituted triazolotriazine (15) was attained.

1,2,4-Triazines. 5. Regioselective N2-Amination of 3-Methylthio-1,2,4-triazin-5(2H)-ones. A New Efficient Synthesis of Triazolotriazin-7(1H)-one (1)

A regioselective synthesis of 2-amino-1,2,4-triazinones (3a-b) is reported, by reaction of 3-methylthio-1,2,4-triazinones (1a-b) with O-(2,4-dinitrophenyl)hydroxylamine (2), as an amino transfer agent.A spectroscopic study and an unequivocal synthesis of 2-amino-4-methyl-6-phenyl-1,2,4-triazinone (8a) has shown the site of amination to be N2 of the 1,2,4-triazinone ring.Subsequent reaction of 2-amino-1,2,4-triazinone (3b) with ammonium hydroxide, folloved by ring closure with formic acid provided triazolotriazin-7 (1H)-one (10).