852805-34-6

Basic information

• Product Name: (S)-5-(2-allylphenoxymethyl)-1,3-oxazolidin-2-one
• CAS NO: 852805-34-6
• Molecular Weight: 233.267
• Mol File: 852805-34-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-5-(2-allylphenoxymethyl)-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-(2-allylphenoxymethyl)-1,3-oxazolidin-2-one(852805-34-6)
• EPA Substance Registry System: (S)-5-(2-allylphenoxymethyl)-1,3-oxazolidin-2-one(852805-34-6)

Safety Data

• Hazardous Substances Data: 852805-34-6(Hazardous Substances Data)

Upstream product

• 852805-32-4 (S)-4-(2-allylphenoxy)-3-hydroxybutanamide 

Downstream Products

• 23846-71-1 (S)-alprenolol 

Relevant articles and documents

New chemoenzymatic pathway for β-adrenergic blocking agents

The lipase mediated kinetic resolution of pharmaceutically important β-hydroxy nitriles is described in high enantiomeric excesses and good yields. Some of the chiral β-hydroxy nitriles have been employed in the synthesis of β-adrenergic blocking agents such as propranolol, alprenolol and moprolol. This protocol has also been extended for the enantiopure preparation of 5-(4-tosyloxymethyl)-1,3-oxazolidine-2-one and 3-hydroxy-4-tosyloxybutanenitrile, chiral intermediates of high synthetic value.