85287-64-5

Usage

Uses

Used in Fragrance Industry:
(4S)-2,2-Dimethyl-1,3-dioxane-4-methanol is used as a fragrance ingredient for its sweet, floral scent, enhancing the aroma of various consumer products.
Used in Cosmetics and Personal Care Products:
(4S)-2,2-Dimethyl-1,3-dioxane-4-methanol is used as a component in the production of cosmetics, perfumes, and other personal care products, contributing to their pleasant scent and overall sensory experience.
Used in Pharmaceutical Industry:
(4S)-2,2-Dimethyl-1,3-dioxane-4-methanol is used as a building block for the synthesis of various pharmaceutical compounds, leveraging its specific structural and chemical properties as a 4S stereoisomer to create novel and effective medications.

Upstream product

• 42890-76-6 (S)-1,2,4-butanetriol 
• 67-64-1 acetone 
• 32233-44-6 2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acetaldehyde 
• 77-76-9 2,2-dimethoxy-propane 
• 85287-65-6 3,5-dinitrobenzoate of (3S)-3,4-(isopropylidenedioxy)butan-1-ol 
• 105183-43-5 ((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-acetic acid 2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl ester 
• 94339-91-0 ethyl (S)-2-hydroxy-4-(1',1'-dimethyl-1'-methoxy)methoxybutanoate 
• 3068-00-6 D,L-1,2,4-butanetriol 
• 32233-43-5 2-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanol 
• 94339-92-1 ethyl (S)-2,4-dihydroxybutanoate 2,4-acetonide 
• 66348-33-2 (S)-1,2,4-butanetriol 2-(1-methyl-1-methoxyethyl ether) 
• 94339-90-9 ethyl (S)-2-acetoxy-4-(1',1'-dimethyl-1'-methoxy)methoxybutanoate 
• 66348-32-1 (S)-diethyl malate 2-(1-methyl-1-methoxyethyl ether) 

Downstream Products

• 94339-93-2 (S)-butane-1,2,4-triol 2,4-acetonide 1-tosylate 
• 195257-54-6 (4S)-4-(2-[(4-methoxybenzyl)oxy]ethyl)-2,2-dimethyl-1,3-dioxolane 
• 180-84-7 (R)-1,7-dioxaspiro[5.5]undecane 
• 180-84-7 (R)-(-)-1,7-dioxaspiro<5.5>undecane 
• 180-84-7 (S)-(+)-1,7-dioxaspiro<5.5>undecane 
• 85287-66-7 3,5-Dinitro-benzoic acid (S)-2,2-dimethyl-[1,3]dioxan-4-ylmethyl ester 

Relevant academic research and scientific papers

IMMUNOMODULATORY GLYCOSPHINGOLIPIDS AND METHODS OF USE THEREOF

Provided herein are a subset of alpha-galactosylceramide (alpha-GC) compounds having improved immunomodulatory activity, particularly with respect to NKT cell number and activity. Also provided herein are methods of use of such compounds, including in the modulation of NKT cells and/or activity in vivo. Further provided are combinatorial synthesis methods for generating alpha-GC compounds of specifically defined structure and thereby generating pure preparations thereof.

SYNTHESIS OF THE OPTICALLY ACTIVE FORMS OF 4,10-DIHYDROXY-1,7-DIOXASPIROUNDECANE AND THEIR CONVERSION TO THE ENANTIOMERS OF 1,7-DIOXASPIROUNDECANE, THE OLIVE FLY PHEROMONE

Both the enantiomers of 1,7-dioxaspiroundecane, the major component of the pheromone of the olive fly (Dacus oleae), were synthesized from (S)-malic acid.

SYNTHESIS OF THE ENANTIOMERS OF 1,7-DIOXASPIROUNDECANE AND 4-HYDROXY 1,7-DIOXASPIROUNDECANE, THE COMPONENTS OF THE OLIVE FLY PHEROMONE

The enantiomers of the olive fly pheromone (1 and 4) were synthesized from (S)-malic acid in amounts sufficient for the biological test.

Facile access to (S)-1,2,4-butanetriol and its derivatives

The synthesis of (S)-1,2,4-butanetriol from the readily available (S)-malic acid in one step using borane-dimethyl sulfide is described.

ON THE FORMATION OF THE 1,2-ACETONIDE OF (+), (-), AND (+/-) 1,2,4-BUTANETRIOL AND ITS CORRESPONDING ALDEHYDE

The acetonides 1 and 3 are components of a 9:1 equilibrium established during their formation.