85293-46-5

Usage

Uses

Used in Pharmaceutical Industry:
1-tert-Butyl 3-Methyl 2,2-diMethylMalonate is used as an intermediate in the synthesis of pharmaceuticals, particularly for the production of antineoplastic agents. It plays a crucial role in the development of medications that combat various types of cancer.
Used in Agrochemical Industry:
In the agrochemical sector, 1-tert-Butyl 3-Methyl 2,2-diMethylMalonate is utilized as an intermediate in the synthesis of herbicides. Its incorporation aids in the creation of effective weed control agents for agricultural applications.
Used in Fine Chemicals Production:
1-tert-Butyl 3-Methyl 2,2-diMethylMalonate is also employed in the creation of other fine chemicals, highlighting its broad applicability in the chemical industry and its significance as a versatile building block for various chemical compounds.

InChI:InChI=1/C10H18O4/c1-9(2,3)14-8(12)10(4,5)7(11)13-6/h1-6H3

Upstream product

• 49761-82-2 tert-butyl 1H-imidazole-1-carboxylate 
• 74-88-4 methyl iodide 
• 42726-73-8 methyl t-butyl malonate 

Downstream Products

• 25307-76-0 tert-butyl 3-hydroxy-2,2-dimethylpropanoate 
• 25307-79-3 tert-butyl 2,2-dimethyl-3-(tosyloxy)propanoate 

Relevant academic research and scientific papers

DIHYDROPYRIMIDINE DERIVATIVES AND USES THEREOF IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES

The application describes dihydropyrimidine derivatives which are useful in the treatment or prevention of HBV infection or of HBV-induced diseases, more particularly of HBV chronic infection or of diseases induced by HBV chronic infection, as well as pharmaceutical or medical applications thereof.

DERIVATIVES OF RELEBACTAM AND USES THEREOF

Derivatives of relebactam, therapeutic methods of using the derivatives of relebactam, particularly in combination with β-lactam antibiotics and pharmaceutical compositions thereof are disclosed. The derivatives of relebactam are suitable for oral administration.

HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

AZTREONAM DERIVATIVES AND USES THEREOF

Disclosed herein are aztreonam derivatives, therapeutic methods of using the aztreonam derivatives, particularly in combination with β-lactamase inhibitors, and pharmaceutical compositions thereof. The aztreonam derivatives can be administered orally to provide orally bioavailable aztreonam.

Beta-lactamase inhibitors and uses thereof

β-Lactamase inhibiting compounds, therapeutic methods of using the β-lactamase inhibiting compounds, particularly in combination with β-lactam antibiotics and pharmaceutical compositions thereof are disclosed. The β-lactamase inhibiting compounds are suitable for oral administration.

AROMATIC HETEROCYCLIC COMPOUND

The compound represented by the general formula: wherein ring A is benzene which may be substituted and the like; ring B is benzene which may be substituted and the like; X is a single bond and the like; Y is alkyl which may be substituted and the like; Z is CR1 or nitrogen atom; R1 is hydrogen and the like; R2 is alkyl which may be substituted and the like or a pharmaceutically acceptable salt thereof is useful as a prevention/treatment agent of obesity, diabetes, and the like.

A PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES

The present invention is to provide a process for preparing optically active tetrahydroquinoline derivatives which can be used for the treatment and/or prevention of diseases such as arteriosclerotic diseases, dyslipidemia and the like, and a process for preparing synthetic intermediates thereof. Specifically, (2R,4S)-2-ethyl-6-trifluoromethyl-1,2,3,4-tetrahydroquinolin-4-ylamine or a salt thereof is prepared with fewer steps without using an optical resolution, and the optically active tetrahydroquinoline derivatives are obtained from the amine compound.

REACTIVITE DU N,N'-CARBONYLDIIMIDAZOLE ET DE SES DERIVES VIS-A-VIS DE L'ENOLATE DE LITHIUM DE L'ISOBUTYRATE DE METHYLE

Functionalization of methyl isobutyrate can be performed through its enolate condensation with N,N'-carbonyldiimidazole and several of its derivatives.