852950-13-1

Basic information

• Product Name: 2,6-dimethyl-4-methylsulfanylphenoxytriisopropylsilane
• Synonyms: 2,6-dimethyl-4-methylsulfanylphenoxytriisopropylsilane
• CAS NO: 852950-13-1
• Molecular Weight: 324.603
• Mol File: 852950-13-1.mol

Chemical Properties

• CAS DataBase Reference: 2,6-dimethyl-4-methylsulfanylphenoxytriisopropylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethyl-4-methylsulfanylphenoxytriisopropylsilane(852950-13-1)
• EPA Substance Registry System: 2,6-dimethyl-4-methylsulfanylphenoxytriisopropylsilane(852950-13-1)

Safety Data

• Hazardous Substances Data: 852950-13-1(Hazardous Substances Data)

Upstream product

• 2374-05-2 4-bromo-2,6-dimethyl-phenol 
• 624-92-0 Dimethyldisulphide 
• 852950-12-0 (4-bromo-2,6-dimethylphenoxy)triisopropylsilane 

Downstream Products

• 852950-17-5 diethyl [3,5-dimethyl-4-(4'-methoxy-3'-isopropylphenoxy)benzenesulfonyl]methylphosphonate 
• 852950-15-3 diethyl (3,5-dimethyl-4-triisopropylsilanyloxy-benzenesulfonyl)methylphosphonate 
• 852950-16-4 diethyl (3,5-dimethyl-4-hydroxybenzenesulfonyl)methylphosphonate 
• 852950-20-0 (4-chloromethylsulfanyl-2,6-dimethylphenoxy)triisopropylsilane 
• 852950-14-2 (2,6-dimethyl-4-methanesulfonylphenoxy)triisopropylsilane 

Relevant articles and documents

Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs

Phosphonic acid (PA) thyroid hormone receptor (TR) agonists were synthesized to exploit the poor distribution of PA-based drugs to extrahepatic tissues and thereby to improve the therapeutic index. Nine PAs showed excellent TR binding affinities (TRβ

NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS

The present invention relates to compounds of phosphonic acid containing T3 mimetics, stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and pharmaceutically acceptable salts and co-crystals of the prodrugs, as well as their preparation and uses for preventing and/or treating metabolic diseases such as obesity, NASH, hypercholesterolemia and hyperlipidemia, as well as associated conditions such as atherosclerosis, coronary heart disease, impaired glucose tolerance, metabolic syndromex and diabetes.