853017-78-4Relevant articles and documents
An approach towards the synthesis of sialyl nucleoside mimetics
Grice, I. Darren,Whelan, Catherine,Tredwell, Gregory D.,Von Itzstein, Mark
, p. 1425 - 1434 (2005)
An approach towards the synthesis of novel sialyl nucleoside mimetics based on d-fructose is described. The synthesis of these mimetics is achieved in good overall yield in seven steps. The key synthetic step is the coupling reaction of pyrimidine bases (uracil, 5-fluorouracil and cytosine) to the C-1 position of the modified D-tagatofructofuranoside.