853020-71-0

Usage

Chemical structure

Pyrrolidine derivative with a phenoxyethyl group attached to the nitrogen atom

Industry application

Pharmaceutical industry

Function

Neurotransmitter modulator

Potential uses

Anti-inflammatory and analgesic agent

Upstream product

• 40499-83-0 pyrrolidin-3-ol 
• 589-10-6 phenoxyethyl bromide 

Downstream Products

• 853018-60-7 ethyl ({[7-fluoro-1'-(2-phenoxyethyl)-4,9-dihydrospiro[β-carboline-1,3'-pyrrolidin]-2(3H)-yl]carbonyl}amino)acetate trifluoroacetate 
• 853020-70-9 1-(2-phenoxyethyl)pyrrolidin-3-one 

Relevant academic research and scientific papers

NOVEL BETA-CARBOLINES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR (GHSR) ANTAGONISTS

The present invention relates to compounds of Formula (I): Formula (I) wherein R-R, X, and Y are as described herein, processes for preparing the compounds, pharmaceutical compositions comprising the compounds, and use of the compounds and compositions in the prophylaxis or treatment of a GHSR receptor-related disorder. Examples of such disorders are obesity and related disorders such as diabetes type II, dyslipidemia and the metabolic syndrome Prader-Willi syndrome, cardiovascular diseases such as atherosclerotic vascular disease, angina pectoris, myocardial infarction and stroke, acromegaly and cancer, in particular breast, lung, prostate, thyroid and endocrine pituary carcinomas.