85311-78-0

Basic information

• Product Name: 2-(Methyl-phenyl-amino)-6-phenyl-[1,3]thiazin-4-one
• CAS NO: 85311-78-0
• Molecular Weight: 294.377
• Mol File: 85311-78-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(Methyl-phenyl-amino)-6-phenyl-[1,3]thiazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Methyl-phenyl-amino)-6-phenyl-[1,3]thiazin-4-one(85311-78-0)
• EPA Substance Registry System: 2-(Methyl-phenyl-amino)-6-phenyl-[1,3]thiazin-4-one(85311-78-0)

Safety Data

• Hazardous Substances Data: 85311-78-0(Hazardous Substances Data)

Upstream product

• 75861-69-7 trans-3-Phenylpropenoyl isothiocyanate 
• 100-61-8 N-methylaniline 
• 120681-15-4 3-Chloro-3-phenylpropenoyl Chloride 
• 18819-66-4 (Z)-3-chloro-3-phenyl-2-propenoic acid 
• 85311-60-0 3-Chloro-3-phenylpropenoyl Isothiocyanate 

Relevant articles and documents

Addition-Cyclization Reactions of Cinnamoyl Isothiocyanate with Nitrogen and Oxygen Nucleophiles

Bithiourea 2 obtained from isothiocyanate 1 and thiosemicarbazide was cyclized to yield triazolopyrimidine (5). Addition cyclization of dibenzylamine or N-methylaniline and compound 1 gave thiazines 7a,b. Refluxing of 1 and sodium ethoxide provided thiazine 8. Reaction of hydrazine and isothiocyanate 1 afforded triazole 12 that reacted with malononitrile or 1,3-cyclohexanedione to give triazolopyridine 14 and triazoloquinoline 16 respectively. The synthesis of triazolothiazine 19 is also described.