75861-69-7

Upstream product

• 1858-25-9 phosphoryl-isothiocyanate 
• 140-10-3 (E)-3-phenylacrylic acid 
• 102-92-1 Cinnamoyl chloride 
• 333-20-0 potassium thioacyanate 
• 1147550-11-5 ammonium thiocyanate 

Downstream Products

• 78374-80-8 1-(N-3-phenylpropenoyl)thiocarbamoylpiperidine 
• 125746-10-3 1-[4-Methyl-2-((E)-styryl)-6-thioxo-1,6-dihydro-pyrimidin-5-yl]-ethanone 
• 75861-63-1 acetone 2-phenyl-4-(3-phenylpropenoyl)thiosemicarbazone 
• 116719-72-3 (E)-N-[4-Benzylsulfanyl-6-((E)-styryl)-[1,3,5]triazin-2-yl]-3-phenyl-acrylamide 
• 116719-69-8 (E)-N-{(2-Benzyl-isothioureido)-[(E)-(E)-(3-phenyl-acryloyl)imino]-methyl}-3-phenyl-acrylamide 
• 115983-11-4 N-(3-phenylpropenoyl)-N'-(3-trifluoromethyl-phenyl)thiourea 
• 78374-76-2 N-cyclohexyl-N'-3-phenylpropenoylthiourea 
• 89373-80-8 N-(4-Nitrophenyl)-N'-3-phenylpropenoylthiourea 
• 75861-67-5 1-phenyl-3-phenylvinyl-5-methylthio-1,2,4-triazole 
• 75614-61-8 1-phenyl-4-(3-phenylpropenoyl)-S-methylisothiosemicarbazide 
• 538-56-7 3-phenylpropenoic anhydride 
• 89373-82-0 N-(3-Methylphenyl)-N'-3-phenylpropenoylthiourea 
• 89373-83-1 N-(3-Bromophenyl)-N'-3-phenylpropenoylthiourea 
• 89373-79-5 N-(4-Bromophenyl)-N'-3-phenylpropenoylthiourea 

Relevant academic research and scientific papers

Synthesis and Antimicrobial Activity of Polyfunctionally Substituted Heterocyclic Compounds Derived from 5-Cinnamoylamino-2-Cyanomethyl-1,3,4-Thiadiazole

Cinnamoyl isothiocyanate 1 was reacted with 2-cyanoethanoic acid hydrazide 2 to afford 1-cyanoacetyl-4-substituted thiosemicarbazide 3, which on treatment with a mixture of glacial acetic acid and acetic anhydride gave the desired 5-cinnamoylamino-2-cyanomethyl-1,3,4-thiadiazole 4. Compound 4 was subjected to react with aromatic aldehydes, phenylisothiocyanate, carbon disulphide, and arylidene malononitrile to give coumarin 5, thiazolidines 8,9, and 1,3,4-thiadiazolo[3,2-a]pyridine 13 derivatives. The structures of all synthesized compounds were ascertained by spectral and analytical data. Antimicrobial activity of some of prepared compounds was investigated, and compounds 7, 8 were found to exhibit the highest strength.

Synthesis, Structure, and Biological Activity of Cinnamoyl-Containing Cytisine and Anabasine Alkaloids Derivatives

The reactions of the cytisine and anabasine alkaloids with cinnamic acid chloride have been studied, and hydrazinolysis of the resulting N-cinnamoylcytisine and N-cinnamoylanabazine has been carried out. The reaction of cinnamoyl isothiocyanate with alkal

Thiourea derivatives, and preparation method and application thereof

The invention relates to thiourea derivatives represented by formula I, pharmaceutically acceptable salts thereof and a pharmaceutical composition thereof, and an application of the thiourea derivatives in the preparation of an influenza virus neuraminida

Synthesis and Intramolecular Heterocyclization of Selected Isonicotinic Acid Thiocarbazides

The reaction of isonicotinic acid hydrazide with ethyl-, allyl-, and cinnamoyl isothiocyanates has afforded the corresponding alkylthiosemicarbazides and the products of their intramolecular heterocyclization, 1,2,4-triazoles.

Heterocyclization of isoniazid: Synthesis and antimicrobial activity of some new pyrimidine, 1, 3-thiazole, 1, 2, 4-thiadiazole, and 1, 2, 4-triazole derivatives derived from isoniazid

THE (2) affordedREACTION cinnamoylof isonicotinic thiosemicarbazidehydrazide derivative\(1)(isoniazid) 3. Treatmentwith cinnamoyl of 3 withisothiocyanate lead acetate

Intermolecular cyclization of cinnamoyl isothiocyanate: A new synthetic entry for pyrimidine, triazine, and triazole candidates

An efficient and facile protocol for the synthesis of azine and azole ring systems was reported. Whereas, reaction of cinnamoyl isothiocyanate with N-nucleophile containing compounds (namely, p-aminophenol (2), N1-phenylbenzene-1,4-diamine (5)

Synthesis, spectral and single-crystal analyses of new derivatives of 4-amino-N-benzylpiperidine

Two new compounds of thiourea derivatives of cinnamoyl and benzoylisothiocyanate with 4-amino-N-benzylpiperidine have been successfully synthesized. The new molecules, 1-(1-benzylpiperidine-4-yl)-3-benzoyl thiourea (I) (yield 83 %) and 1-(1-benzylpiperidi

Efficient synthesis of new (R)-2-amino-1-butanol derived ureas, thioureas and acylthioureas and in vitro evaluation of their antimycobacterial activity

The synthesis of 22 structurally diverse urea, thiourea and acylthiourea derivatives containing the (R)-2-amino-1-butanol motif has been performed. The evaluation of their in vitro activity against Mycobacterium tuberculosis (H 37Rv and strain

A Convenient Synthesis of Tertiary Isothiocyanates and Acyl Isothiocyanates Using Phosphoryl Isothiocyanate.

Phosphoryl iosthiocyanate, PO(NCS)3, reacts readily with tertiary alcohols and carboxylic acids, giving the respective tertiary isothiocyanates and acyl isothiocyanates in good yields and purity.