75861-69-7

Basic information

• Product Name: 2-Propenoyl isothiocyanate, 3-phenyl-, (2E)-
• CAS NO: 75861-69-7
• Molecular Formula: C10H7NOS
• Molecular Weight: 189.238
• Mol File: 75861-69-7.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Propenoyl isothiocyanate, 3-phenyl-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoyl isothiocyanate, 3-phenyl-, (2E)-(75861-69-7)
• EPA Substance Registry System: 2-Propenoyl isothiocyanate, 3-phenyl-, (2E)-(75861-69-7)

Safety Data

• Hazardous Substances Data: 75861-69-7(Hazardous Substances Data)

Upstream product

• 1858-25-9 phosphoryl-isothiocyanate 
• 140-10-3 (E)-3-phenylacrylic acid 
• 333-20-0 potassium thioacyanate 
• 102-92-1 Cinnamoyl chloride 
• 1147550-11-5 ammonium thiocyanate 

Downstream Products

• 125746-10-3 1-[4-Methyl-2-((E)-styryl)-6-thioxo-1,6-dihydro-pyrimidin-5-yl]-ethanone 
• 75861-63-1 acetone 2-phenyl-4-(3-phenylpropenoyl)thiosemicarbazone 
• 116719-72-3 (E)-N-[4-Benzylsulfanyl-6-((E)-styryl)-[1,3,5]triazin-2-yl]-3-phenyl-acrylamide 
• 116719-69-8 (E)-N-{(2-Benzyl-isothioureido)-[(E)-(E)-(3-phenyl-acryloyl)imino]-methyl}-3-phenyl-acrylamide 
• 1442093-68-6 (R)-N-(1-hydroxybutan-2-ylcarbamothioyl)cinnamamide 
• 115983-11-4 N-(3-phenylpropenoyl)-N'-(3-trifluoromethyl-phenyl)thiourea 
• 78374-80-8 1-(N-3-phenylpropenoyl)thiocarbamoylpiperidine 

Relevant articles and documents

Synthesis and Antimicrobial Activity of Polyfunctionally Substituted Heterocyclic Compounds Derived from 5-Cinnamoylamino-2-Cyanomethyl-1,3,4-Thiadiazole

Cinnamoyl isothiocyanate 1 was reacted with 2-cyanoethanoic acid hydrazide 2 to afford 1-cyanoacetyl-4-substituted thiosemicarbazide 3, which on treatment with a mixture of glacial acetic acid and acetic anhydride gave the desired 5-cinnamoylamino-2-cyanomethyl-1,3,4-thiadiazole 4. Compound 4 was subjected to react with aromatic aldehydes, phenylisothiocyanate, carbon disulphide, and arylidene malononitrile to give coumarin 5, thiazolidines 8,9, and 1,3,4-thiadiazolo[3,2-a]pyridine 13 derivatives. The structures of all synthesized compounds were ascertained by spectral and analytical data. Antimicrobial activity of some of prepared compounds was investigated, and compounds 7, 8 were found to exhibit the highest strength.

Thiourea derivatives, and preparation method and application thereof

The invention relates to thiourea derivatives represented by formula I, pharmaceutically acceptable salts thereof and a pharmaceutical composition thereof, and an application of the thiourea derivatives in the preparation of an influenza virus neuraminida

Heterocyclization of isoniazid: Synthesis and antimicrobial activity of some new pyrimidine, 1, 3-thiazole, 1, 2, 4-thiadiazole, and 1, 2, 4-triazole derivatives derived from isoniazid

THE (2) affordedREACTION cinnamoylof isonicotinic thiosemicarbazidehydrazide derivative\(1)(isoniazid) 3. Treatmentwith cinnamoyl of 3 withisothiocyanate lead acetate