85322-17-4

Upstream product

• 13176-46-0 4-bromoethyl acetoacetate 
• 5373-87-5 4-methoxybenzamidoxime 

Downstream Products

• 99141-46-5 [6-Methoxy-2-(4-methoxy-phenyl)-pyrimidin-4-yl]-methanol 
• 84446-01-5 6-Hydroxymethyl-2-(4-methoxy-phenyl)-pyrimidin-4-ol 
• 84446-07-1 4-Hydroxy-3-[(Z)-4-methoxy-benzimidoylimino]-butyric acid ethyl ester 
• 103677-59-4 3-[(E)-N-Hydroxy-4-methoxy-benzimidoylimino]-butyric acid ethyl ester 
• 84446-01-5 6-Hydroxymethyl-2-p-methoxyphenyl-4-pyrimidinone 
• 84446-02-6 [2-(4-Methoxy-phenyl)-oxazol-4-yl]-acetic acid ethyl ester 

Relevant academic research and scientific papers

Reaction of γ-Bromoacetoacetyl Compounds with Benzamide Oxime Derivatives: Synthesis of 4H-1,2,4-Oxadiazine derivatives.

Reaction of benzamide oxime derivatives (1) with ethyl γ-bromoacetoacetate in the presence of an acidic catalyst gave a mixture of geometrical isomers of 3-aryl-5-ethoxycarbonylmethylene-5,6-dihydro-4H-1,2,4-oxadiazine derivatives (5) in 60-75percent yiel