85330-63-8

Usage

Uses

Used in Pharmaceutical Industry:
2,5-BIS(METHYLSULFONYL)PYRIDINE is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its role in this industry is crucial for creating the foundational structures of potential medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,5-BIS(METHYLSULFONYL)PYRIDINE is employed as a component in the production of agrochemicals, such as pesticides and herbicides. Its integration into these products helps in the development of more effective and targeted agricultural solutions.
Used as a Reagent in Organic Synthesis:
2,5-BIS(METHYLSULFONYL)PYRIDINE is used as a reagent in organic synthesis processes, where it aids in the formation of new compounds through chemical reactions. Its versatility in these reactions makes it a valuable tool in the synthesis of a wide range of organic compounds.
Used as a Methanesulfonylation Agent:
2,5-BIS(METHYLSULFONYL)PYRIDINE is utilized as a mild, selective, and efficient methanesulfonylation agent for a broad spectrum of organic compounds. This application is significant in the modification of organic molecules, allowing for the introduction of specific functional groups and enhancing the properties of the resulting compounds.
Used in the Synthesis of Biologically Active Compounds:
2,5-BIS(METHYLSULFONYL)PYRIDINE is employed as a key intermediate in the synthesis of biologically active compounds, playing a pivotal role in the creation of molecules with potential applications in medicine, biotechnology, and other life sciences. Its presence in these syntheses is essential for the development of novel and effective biological agents.

InChI:InChI=1/C7H9NO4S2/c1-13(9,10)6-3-4-7(8-5-6)14(2,11)12/h3-5H,1-2H3

Upstream product

• 85330-62-7 2,5-bis(methylsulfanyl)pyridine 
• 624-28-2 2,5-dibromopyridine 
• 5188-07-8 sodium thiomethoxide 
• 1702-17-6 Clopyralid 
• 1532-24-7 methyl 3,6-dichloro-2-pyridinecarboxylate 
• 85330-61-6 3,6-bis-methylthiopyridine-2-carboxylic acid 
• 85330-65-0 2,5-bis-methylethylthiopyridine 
• 51933-78-9 5-bromo-2-(methylsulfanyl)pyridine 

Downstream Products

• 103058-99-7 3-[2-chloro-5-(methylsulfonyl)-3-pyridinyl]-1-(3,4-dichlorophenyl)propan-1-ol 
• 103058-94-2 3-<2-Methoxy-5-(methylsulfonyl)-3-pyridinyl>-1-(3,4-dichlorophenyl)-propan-1-one 
• 103058-98-6 3-<2-Chloro-5-(methylsulfonyl)-3-pyridinyl>-1-(3,4-dichlorophenyl)propan-1-one 
• 102830-69-3 2-(3,4-Dichlorophenyl)-3,4-dihydro-6-(methylsulfonyl)-2H-pyrano<2,3-b>pyridine 
• 721430-01-9 2-ethoxy-5-methylsulfonylpyridine 
• 605681-82-1 C₁₂H₁₇NO₅S 
• 18085-51-3 5-methanesulfonyl-1H-pyridin-2-one 
• 142-08-5 2-Pyridone 
• 99902-97-3 2-(3,4-dichlorophenoxy)-5-(methylsulfonyl)pyridine 

Relevant academic research and scientific papers

HETEROARYLCARBAMOYLBENZENE DERIVATIVE

Compounds having glucokinase activating effects and being useful as treatments for diabetes, which are represented by the following formula (I): [wherein X1 represents oxygen, etc., X2 represents oxygen, etc., R1 represents a group on Ring A such as alkylsulfonyl, etc., R2 represents C3-7 cyclic alkyl optionally substituted with a halogen, etc., R3 represents a substituent on Ring B such as lower alkyl, etc., formula (II): represents 6- to 10-membered aryl, etc., and formula (III): represents monocyclic or bicyclic heteroaryl optionally having on Ring B a substituent represented by R3 above, wherein the carbon atom of Ring B which is bonded to the nitrogen atom of the amide group of formula (I) forms a C=N bond with the nitrogen atom of the ring], as well as their pharmaceutically acceptable salts.

Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents

The present invention relates to compounds of the formula wherein R2, R3, R6and A are defined as in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as osteoarthritis, rheumatoid arthritis, colon cancer and Alzheimer's disease, in mammals (preferably humans, dogs, cats and livestock).

2,5-bis alkyl sulfonyl and 2,5-bis alkyl thio substituted-pyridines

A process for preparing substituted-pyridines having a sulfonyl type substituted at the 3 or 5 position of the pyridine ring and a phenoxy type substituent at the 2 position is described.

THE REACTIONS OF SOME HALOGENATED PYRIDINES WITH METHOXYDE AND METHANETHIOLATE IONS IN DIMETHYLFORMAMIDE

The reactions of 2,6- and 2,5-dibromopyridines and of 2,3- and 3,5-dichloropyridines with sodium isopropanethiolate and methanethiolate afforded the products of mono- or of bis-substitution depending on the experimental conditions.The same pyridines reacted with sodium methoxide to give good yields of the mono-substituted products; bis-substitution occurred easily only in the case of the 2,6-dibromo- and of the 3,5-dichloropyridine.The syntheses of some methoxy thiomethoxypyridine, starting from the halogeno methoxypyridines or from the halogeno thiomethoxypyridines are also described.The bis-(alkylthio)pyridines can be fragmented by sodium in HMPA to give the bis(mercapto)pyridines.

bis-Alkylsulfonylpyridines

Dihalogenated pyridines, some activated with carboxylic, ester or cyano group, were allowed to react with sodium alkylmercaptides.After hydrolysis of the ester or cyano group followed by decarboxylation, bis-alkylthiopyridines with substituents at 2,3-, 2,4-, 2,5-, 2,6- and 3,5-positions were prepared.These compounds were oxidized to bis-alkylsulfonylpyridines.

Sulfur-substituted phenoxypyridines having antiviral activity

Sulfur-substituted phenoxypyridines having antiviral activity are disclosed. Methods of using the sulfur-substituted phenoxypyridines to employ their antiviral activity are also disclosed as well as pharmaceutically-acceptable compositions thereof.