853310-45-9Relevant academic research and scientific papers
Synthesis of 1,2,4,5-Tetrasubstituted imidazoles using sulfuric acid ([3-(3-Silicapropyl)sulfanyl]propyl]ester as a recyclable solid acid
Tavakoli, Ziba,Bagherneghad, Mojtaba,Niknam, Khodabakhsh
, p. 634 - 639 (2012)
Sulfuric acid ([3-(3-silicapropyl)sulfanyl]propyl]ester (SASPSPE) is used as a recyclable catalyst for the synthesis of 1,2,4,5-tetrasubstituted imidazoles. A range of various polysubstituted imidazoles was synthesized via four-component condensation of benzil, aldehydes, amines, and ammonium acetate in the presence of SASPSPE under solvent-free conditions at 140°C. The heterogeneous catalyst was recycled for five runs on the reaction of benzil, 4-methylbenzaldehyde, benzyl amine, and ammonium acetate without losing its catalytic activity.
Facile fabrication of porous magnetic covalent organic frameworks as robust platform for multicomponent reaction
Azizi, Najmedin,Heidarzadeh, Fatemeh,Farzaneh, Fezeh
, (2021/07/26)
The design of cheap yet efficient nanoporous magnetic catalysts for the environmentally benign process's widespread application is an extremely attractive, challenging chemical research field. A novel porous magnetic covalent organic framework was prepared by the condensation reaction of melamine and terephthaladehyde on the surface of 3,4-dihydroxybenzaldehyde coated magnetic Fe3O4 nanoparticles COF@Fe3O4 under hydrothermal conditions for the first time. The high surface area magnetic COF could exhibit superior catalytic activity for sustainable synthesis of trisubstituted and tetrasubstituted imidazoles and pyrroles in good to excellent yields in PEG as solvent under environmentally friendly, ambient conditions and making the overall process economical, efficient, and green. The retrievable catalyst in PEG is general and applicable to a broad substrate scope and functional group compatibility. The structure and morphology of the COF@Fe3O4 were characterized by FTIR, XRD, EDX, and SEM spectroscopy. The COF@Fe3O4 magnetic catalyst was recovered by an external magnet and used for several cycles without significant catalytic activity loss.
