853406-76-5Relevant academic research and scientific papers
Structural mimicry of two cytochrome b562 interhelical loops using macrocycles constrained by oxazoles and thiazoles
Singh, Yogendra,Stoermer, Martin J.,Lucke, Andrew J.,Guthrie, Tom,Fairlie, David P.
, p. 6563 - 6572 (2007/10/03)
A major chemical challenge is the structural mimicry of discontinuous protein surfaces brought into close proximity through polypeptide folding. We report the design, synthesis, and solution structure of a highly functionalized saddle-shaped macrocyclic s
