85355-69-7Relevant academic research and scientific papers
Palladium-free Sonogashira-type cross-coupling reaction of bromoisoxazolines or N-alkoxyimidoyl bromides and alkynes
Probst,Deprez,Willand
, p. 1066 - 1070 (2016)
A Cu(I)-catalysed Sonogashira-type cross coupling reaction with aliphatic or aromatic bromoisoxazolines or N-alkoxyimidoyl bromides and alkynes is reported. The protocol we developed employs catalytic amount of copper(I), non-toxic ligand bathophenanthroline and is tolerant to a wide range of functional groups and is therefore particulary adapted in the context of drug discovery.
Benzenesulfonylcarbonitrile Oxide. 4. Substitution Reactions of 3-(Phenylsulfonyl)isoxazolines
Wade, P. A.,Yen, H.-K.,Hardinger, S. A.,Pillay, M. K.,Amin, N. V.,et al.
, p. 1796 - 1800 (2007/10/02)
3-(Phenylsulfonyl)isoxazolines, readily obtained from alkenes by cycloaddition with benzenesulfonylcarbonitrile oxide, undergo a variety of substitution reactions.Alkyl, aryl, and acetylenic lithium reagents, cyanide, lithium or sodium alkoxides, and sodi
