85356-29-2

Upstream product

• 26954-48-3 3-Imino-1-phenylimino-2-methyl-1,3-diphenylpropan 
• 138356-06-6 (2R*,6S*)-5-Methyl-2,3,4,6-tetraphenyl-1,2,3,6-tetrahydropyrimidine 
• 138356-04-4 3-imino-1,3,N-triphenyl-2-methylprop-1-enylamine 

Downstream Products

• 85356-41-8 (2S,3R)-3-Amino-2-methyl-1,3-diphenyl-propan-1-one; hydrochloride 
• 97210-96-3 (1S,2R,3S)-3-Amino-2-methyl-1,3-diphenyl-propan-1-ol 
• 97275-75-7 (1R,2R,3S)-3-Amino-2-methyl-1,3-diphenyl-propan-1-ol 
• 85356-36-1 N-1-[2‐methyl‐3‐oxo‐1,3‐diphenylpropyl] acetamide 
• 97211-14-8 5-methyl-4,6-diphenyltetrahydro-1,3-oxazine 
• 97211-09-1 (4R,5S,6S)-5-Methyl-4,6-diphenyl-[1,3]oxazinan-2-one 
• 97211-12-6 1-(carbethoxyamino)-2-methyl-1,3-diphenyl-3-propanol 

Relevant academic research and scientific papers

Stereoselective Synthesis of 1,3-Amino Alcohols and 1,3-Amino Ketones

syn,anti-N-Alkyl-1,3-amino alcohols 2 with three chiral centers are synthesized with high stereoselectivity by reduction of the corresponding anti-N-acylamino ketones 1 with LiAlH4/TiCl4.The intermediate N-acylamino alcohols 3 can be isolated when DIBALH/

Reduction of 1,3-Diimines. A New and General Method of Synthesis of γ-Diamines, β-Amino Ketones, and Derivatives with Two and Three Chiral Centers

1,3-Diimes 1 are easily reduced with Na/i-PrOH to afford unsymmetrical N-substituted γ-diamines 8 in nearly quantitative yields.Since three chiral centers are generated, compounds 8 are isolated as a mixture of diastereoisomers which are easily separated.