853577-59-0

Basic information

• Product Name: 1-(6-hydroxy-2,3,4-trimethoxyphenyl)-2-methylpropan-1-one
• Synonyms: 1-(6-hydroxy-2,3,4-trimethoxyphenyl)-2-methylpropan-1-one
• CAS NO: 853577-59-0
• Molecular Weight: 254.283
• Mol File: 853577-59-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(6-hydroxy-2,3,4-trimethoxyphenyl)-2-methylpropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-hydroxy-2,3,4-trimethoxyphenyl)-2-methylpropan-1-one(853577-59-0)
• EPA Substance Registry System: 1-(6-hydroxy-2,3,4-trimethoxyphenyl)-2-methylpropan-1-one(853577-59-0)

Safety Data

• Hazardous Substances Data: 853577-59-0(Hazardous Substances Data)

Upstream product

• 642-71-7 3,4,5-trimethoxyphenol 
• 79-30-1 isobutyryl chloride 

Downstream Products

• 853577-72-7 3-(4-benzenesulfonyl-phenyl)-8-isobutyl-5,6,7-trimethoxy-2-methyl-chromen-4-one 
• 853577-69-2 8-isobutyl-5,6,7-trimethoxy-2-methyl-3-(4-phenoxy-phenyl)-chromen-4-one 
• 853577-71-6 3-biphenyl-4-yl-8-isobutyl-5,6,7-trimethoxy-2-methyl-chromen-4-one 
• 853577-70-5 4-(8-isobutyl-5,6,7-trimethoxy-2-methyl-4-oxo-4H-chromen-3-yl)-benzoic acid 
• 853577-68-1 8-isobutyl-5,6,7-trimethoxy-3-(4-methoxy-phenyl)-2-methyl-chromen-4-one 
• 853577-67-0 3-(4-chloro-phenyl)-8-isobutyl-5,6,7-trimethoxy-2-methyl-chromen-4-one 
• 853577-65-8 8-isobutyl-5,6,7-trimethoxy-2-methyl-3-phenyl-4H-chromen-4-one 
• 73694-23-2 2-isobutyl-3,4,5-trimethoxy-phenol 

Relevant articles and documents

Structure-based design of flavonoid compounds as a new class of small-molecule inhibitors of the anti-apoptotic Bcl-2 proteins

Structure-based strategy was employed to design flavonoid compounds to mimic the Bim BH3 peptide as a new class of inhibitors of the anti-apoptotic Bcl-2 proteins. The most potent compound, 4 (BI-33), binds to Bcl-2 and Mcl-1 with Ki values of

Efficient synthesis of isoflavone analogues via a Suzuki coupling reaction

Analogues of 3-aryl-8-isobutyl-5,6,7-trihydroxy-2-methyl-4H-chromen-4-one were synthesized with high yields via the Suzuki coupling reaction of 3-iodo-8-isobutyl-5,6,7-trimethoxy-2-methyl-4H-chromen-4-one with different aryl boronic acids.