853658-46-5

Basic information

• Product Name: (5S)-5-ethyl-3-isopropoxy-5-methyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-thione
• Synonyms: (5S)-5-ethyl-3-isopropoxy-5-methyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-thione
• CAS NO: 853658-46-5
• Molecular Weight: 354.491
• Mol File: 853658-46-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5S)-5-ethyl-3-isopropoxy-5-methyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-thione(CAS DataBase Reference)
• NIST Chemistry Reference: (5S)-5-ethyl-3-isopropoxy-5-methyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-thione(853658-46-5)
• EPA Substance Registry System: (5S)-5-ethyl-3-isopropoxy-5-methyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-thione(853658-46-5)

Safety Data

• Hazardous Substances Data: 853658-46-5(Hazardous Substances Data)

Upstream product

• 189954-93-6 (S)-5-ethyl-5-methyl-3-(1-methylethoxy)-4-[(4-methylsulfonyl)phenyl]-3-oxolen-2-one 

Downstream Products

• 853658-51-2 {(7S)-7-ethyl-9-isopropoxy-7-methyl-8-[4-(methylsulfonyl)phenyl]-1,4,6-trioxaspiro[4.4]non-8-en-2-yl}methanol 
• 906538-77-0 N-[(5S)-5-ethyl-3-isopropoxy-5-methyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-ylidene]-L-serine methyl ester 

Relevant articles and documents

Novel approach to pro-drugs of lactones: Water soluble imidate and ortho-ester derivatives of a furanone-based COX-2 selective inhibitor

Interest in water soluble COX-2 inhibitors that can be administered intravenously led to the development of novel pro-drugs of a furanone based COX-2 inhibitor 2. Transforming the lactone moiety of the furanone to an imidate or an ortho-ester with a hydro