853751-10-7Relevant academic research and scientific papers
Synthesis and anticancer activities of some thiazole derivatives
Kayagil, Ismail,Demirayak, Seref
scheme or table, p. 2197 - 2207 (2010/04/24)
In this study, 2-substituted 4-[3/4-(4-arylthiazole-2-yl)aminophenyl] thiazole derivatives and 2-[4-[2-substituted 4-methylthiazole-5-yl]thiazole-2- yl]amino-5-arylidenethiazoline-4-one derivatives have been synthesized. The cytotoxic and/or growth inhibitory effects of the 16 selected compounds were evaluated in vitro against approximately 66 human tumor cell lines derived from nine neoplastic diseases. Some of the compounds were found to act as anticancer agents.
