85378-39-8Relevant academic research and scientific papers
Novel androgen receptor antagonist identified by structure-based virtual screening, structural optimization, and biological evaluation
Chai, Xin,Fu, Weitao,Hou, Tingjun,Li, Dan,Pang, Jinping,Shan, Lvhu,Sheng, Rong,Tang, Qin,Wang, Ercheng,Wang, Xuwen,Xu, Lei,Xu, Xiaohong,Zhang, Minkui
, (2020/02/29)
Androgen receptor (AR) plays important roles in the development of prostate cancer (PCa), and therefore it has been regarded as the most important therapeutic target for both hormone-sensitive prostate cancer (HSPC) and advanced PCa. In this study, a nove
Synthesis of benzo[a]phenanthridine derivatives by condensation of N-arylmethylene-2-naphthylamines with 5-phenyl- and 5-(p-methoxyphenyl)-1,3-cyclohexanediones
Kozlov,Basalaeva,Skakovskaya
, p. 1238 - 1242 (2007/10/03)
Condensation of N-arylmethylene-2-naphthylamines with 5-phenyl- and 5-(p-methoxyphenyl)-1,3-cyclohexanediones in various solvents gave new hexahydrobenzo[a]phenanthridin-4-one derivatives. Three-component condensation of 2-naphthylamine, appropriate aldeh
