853792-27-5Relevant academic research and scientific papers
NAPHTHYLUREA DERIVATIVES AND MEDICAL APPLICATIONS THEREOF
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Paragraph 0047; 0052-0053, (2016/08/17)
The present invention relates to naphthylurea derivatives. Such substances can significantly inhibit VEGFR2 and PDGFR-β receptor tyrosine kinase phosphorylation at nanomolar concentration levels. It is a novel type of tyrosine kinase inhibitors which can be used in the treatment of tyrosine kinase-mediated diseases or symptoms such as malignancies and ocular diseases accompanied with pathologic neovascularization
Boron-Containing Small Molecules as Anti-Inflammatory Agents
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Paragraph 1139, (2015/11/16)
Compounds and methods of treating anti-inflammatory conditions are disclosed.
BORON-CONTAINING SMALL MOLECULES
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Page/Page column 149, (2011/08/21)
Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions and/or helminth-associated diseases are disclosed.
2-AMINOQUINAZOLINE DERIVATIVE
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Page/Page column 28, (2010/11/24)
The present invention provides a compound represented by Formula (I) (wherein R 1 and R 2 are the same or different, and each represents a hydrogen atom, substituted or unsubstituted lower alkyl and the like, R 3 represents substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic group and the like, R 4 and R 5 are the same or different, and each represents a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl and the like, proviso that they are not simultaneously hydrogen atoms, and R 6 represents hydroxy or substituted or unsubstituted lower alkoxy), or a pharmaceutically acceptable salt thereof and the like.
