85386-20-5Relevant academic research and scientific papers
2-AMINOQUINOLINE DERIVATIVE
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Page/Page column 24, (2008/06/13)
This invention provides 2-aminoquinoline derivatives represented by a general formula [I] [in which R1 and R2 either stand for lower alkyl, lower cycloalkyl, etc., or R1 and R2 together form an aliphatic nitroge
IMIDAZOPYRIDINE DERIVATIVES
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Page/Page column 32, (2008/06/13)
The invention provides imidazopyridine derivatives represented by the general formula [I] [in which R1 and R2 may be the same or different and stand for C1-6 alkyl or the like, R3 and R4 stand for hydrogen atom, methyl group or the like, W stands for mono- or bi-cyclic 3- to 8-membered aromatic or aliphatic heterocycle or the like, and Ar stands for optionally substituted aromatic heterocycle or the like]. These compounds act as melanin-concentrating hormone receptor antagonist and are useful as medicines for central nervous system disorders, cardiovascular system disorders and metabolic disorders.
CHEMICAL PROPERTIES OF YLIDENE DERIVATIVES OF AZINES. 7. CONVERSIONS OF 5-METHYL(PHENYL)-SUBSTITUTED 1,2-DIHYDRO-2-PYRIMIDINYLIDENEMALONONITRILES BY NITRIC ACID
Oleinik, I. V.,Zagulyaeva, O. A.
, p. 427 - 431 (2007/10/02)
It has been shown that the reaction of 5-methyl(phenyl)pyrimidinylidenemalononitrile with nitric acid leads either to a 2-pyrimidinecarboxylic acid or to a pyrimidinylidene-α-carboxamido(α-carboxamido, α-nitro)-acetonitrile depending on the conditions.
SYNTHESIS OF 5-ARYLPYRIMIDINE-2-CARBOXYLIC ACIDS AND THE LIQUID-CRYSTAL CHARACTERISTICS OF THEIR ARYL ESTERS
Mikhaleva, M. A.,Kolesnichenko, G. A.,Rubina, K. I.,Gol'dberg, Yu. Sh.,Savel'ev, V. A.,et al.
, p. 310 - 318 (2007/10/02)
5-Arylpyrimidine-2-carboxylic acids were synthesized by the hydrolysis of 5-aryl-2-cyanopyrimidines and the oxidation of 5-aryl-2-styrylpyrimidines under the conditions of phase-transfer catalysis.The aryl esters of the acids were obtained, and their liqu
