853923-30-5

Upstream product

• 115114-87-9 (2R)-2-(2-benzyloxyethyl)oxirane 
• 1220512-09-3 C₁₂H₁₆O₃ 
• 2622-05-1 allylmagnesium bromide 
• 124010-07-7 (4S,6R)-8-(benzyloxy)-6-(tert-butyldimethylsilyloxy)oct-1-en-4-ol 
• 1173106-18-7 (3R,5S)-1-(benzyloxy)-5-{[(tert-butyl)dimethylsilyl]oxy}oct-7-en-3-ol 
• 236427-78-4 (S)-((1-(benzyloxy)hex-5-en-3-yl)oxy)(tert-butyl)dimethylsilane 
• 91285-62-0 (S)-1-(benzyloxy)-3-hydroxyhex-5-ene 
• 853923-25-8 8-benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-oct-1-en-4-one 
• 853923-26-9 8-benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-oct-1-en-4-ol 
• 124010-06-6 (R)-(+)-5-(benzyloxy)-3-(tert-butyldimethylsilyloxy)pentanal 
• 853923-29-2 (R)-8-Benzyloxy-6-hydroxy-oct-1-en-4-one 

Downstream Products

• 853923-24-7 (4S,6S)-4-[2-(benzyloxy)ethyl]-2,2-dimethyl-6-(prop-2-en-1-yl)-1,3-dioxane 
• 853923-23-6 (1S)-2-{(4S,6R)-6-[2-(benzyloxy)ethyl]-2,2-dimethyl-1,3-dioxan-4-yl}-1-methylethyl acetate 
• 876068-24-5 (2S)-1-{(4S,6R)-6-[2-(benzyloxy)ethyl]-2,2-dimethyl-1,3-dioxan-4-yl}propan-2-ol 
• 853923-32-7 (4R,6R)-4-(2-Benzyloxy-ethyl)-2,2-dimethyl-6-oxiranylmethyl-[1,3]dioxane 

Relevant academic research and scientific papers

A facile and efficient synthesis of 4-hydroxy-2,6-c/s-tetrahydropyrans via tandem cross-metathesis/thermal sn2′ reaction: protecting-group-free synthesis of (±)-diospongin A

The tandem cross-metathesis/thermal SN2' reaction was explored for the facile and efficient synthesis of 4-hydroxy-2,6-cis-tetrahydropyrans. The mildness of the thermal conditions allowed for the synthesis of 4-hydroxy-2,6-cis-tetrahydropyrans from base-sensitive substrates without the use of protecting groups. The tandem reaction enabled a protecting-group-free synthesis of (±)-diospongin A.

Elongation of 1,3-polyols via iterative catalyst-directed carbonyl allylation from the alcohol oxidation level

Iterative enantioselective carbonyl allylation from the alcohol oxidation level under the conditions of iridium catalyzed transfer hydrogenation enables chain elongation of 1,3-polyols. High levels of catalyst-directed enantioselectivity and diastereosele

Stereoselective routes for the total synthesis of (+)-cryptocarya diacetate

A stereoselective total synthesis of (+)-cryptocarya diacetate (1) was achieved by two different routes (Schemes 2 and 3). The sequences involve LiAlH4/LiI reduction, ring-closing metathesis, Prins cyclization, Wacker oxidation, and Wittig olefination reactions as key steps.

Stereoselective total synthesis of (+)-cryptocarya diacetate by an iterative Jacobsen's hydrolytic kinetic resolution protocol

A combination of iterative Jacobsen's hydrolytic kinetic resolution and reduction of a ketone for the construction of a 1,3-polyol moiety are key steps en route to a total synthesis of (+)-cryptocarya diacetate.