853929-47-2

Upstream product

• 2930-05-4 (S)-benzyl glycidyl ether 
• 853929-46-1 (S)-1-Benzyloxy-hept-4-yn-2-ol 
• 98-88-4 benzoyl chloride 
• 2930-05-4 Benzyloxymethyl-oxiran 

Downstream Products

• 853929-53-0 Benzoic acid (Z)-(S)-1-formyl-hex-3-enyl ester 
• 853929-62-1 C₃₇H₃₈O₆ 
• 853929-65-4 C₃₇H₄₂O₆ 
• 578008-43-2 7(S),17(S)-resolvin D5 
• 853929-57-4 Benzoic acid (E)-(S)-1-((Z)-pent-2-enyl)-8-trimethylsilanyl-oct-2-ene-4,7-diynyl ester 
• 853929-60-9 Benzoic acid (E)-(S)-((Z)-1-pent-2-enyl)-oct-2-ene-4,7-diynyl ester 
• 853929-51-8 Benzoic acid (Z)-(S)-1-hydroxymethyl-hex-3-enyl ester 

Relevant academic research and scientific papers

First total synthesis of 7(S),17(S)-Resolvin D5, a potent anti-inflammatory docosanoid

The first total synthesis of 7(S),17(S)-Resolvin D5, a lipid mediator derived from docosahexaenoic acid, has been achieved. The chiral centers were generated via a Co-salen hydrolytic kinetic resolution of a terminal epoxide with >99% ee. Key steps include Takai olefination, Pd0/Cu I coupling and simultaneous deprotection and ester cleavage with lipase from Candida rugosa.