854022-39-2

Basic information

• Product Name: {2-[3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-5-methyl-phenyl]-1-formyl-ethyl}-carbamic acid allyl ester
• Synonyms: {2-[3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-5-methyl-phenyl]-1-formyl-ethyl}-carbamic acid allyl ester
• CAS NO: 854022-39-2
• Molecular Weight: 407.582
• Mol File: 854022-39-2.mol

Chemical Properties

• CAS DataBase Reference: {2-[3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-5-methyl-phenyl]-1-formyl-ethyl}-carbamic acid allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {2-[3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-5-methyl-phenyl]-1-formyl-ethyl}-carbamic acid allyl ester(854022-39-2)
• EPA Substance Registry System: {2-[3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-5-methyl-phenyl]-1-formyl-ethyl}-carbamic acid allyl ester(854022-39-2)

Safety Data

• Hazardous Substances Data: 854022-39-2(Hazardous Substances Data)

Upstream product

• 1073536-47-6 (S)-allyl 1,1-bis(ethylthio)-3-(3-tert-butyldimethylsilyloxy-4-methoxy-5-methylphenyl)propan-2-ylcarbamate 
• 686776-20-5 2-amino-3-[4-methoxy-3-methyl-5-(toluene-4-sulfonyloxy)-phenyl]-propionic acid tert-butyl ester 
• 686776-28-3 [(S)-2-(3-Hydroxy-4-methoxy-5-methyl-phenyl)-1-hydroxymethyl-ethyl]-carbamic acid allyl ester 
• 686776-25-0 toluene-4-sulfonic acid 5-hydroxymethyl-2-methoxy-3-methyl-phenyl ester 
• 686776-22-7 3-tolylsulfonyloxy-4-methoxy-5-methyl benzyl bromide 
• 686776-24-9 toluene-4-sulfonic acid 5-formyl-2-methoxy-3-methyl-phenyl ester 
• 686776-27-2 (S)-5-(2-amino-3-hydroxypropyl)-2-methoxy-3-methylphenol 
• 686776-23-8 toluene-4-sulfonic acid 2-methoxy-3-methyl-phenyl ester 
• 244126-22-5 toluene-4-sulfonic acid 2-hydroxy-3-methyl-phenyl ester 
• 488-17-5 3-methylbenzene-1,2-diol 
• 854022-25-6 [2-[3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-5-methyl-phenyl]-1-(tert-butyl-dimethyl-silanyloxymethyl)-ethyl]-carbamic acid allyl ester 
• 854022-23-4 (S)-allyl 1-hydroxy-3-(3-tert-butyldimethylsilyloxy-4-methoxy-5-methylphenyl)propan-2-ylcarbamate 

Downstream Products

• 854022-23-4 (S)-allyl 1-hydroxy-3-(3-tert-butyldimethylsilyloxy-4-methoxy-5-methylphenyl)propan-2-ylcarbamate 
• 1073536-47-6 (S)-allyl 1,1-bis(ethylthio)-3-(3-tert-butyldimethylsilyloxy-4-methoxy-5-methylphenyl)propan-2-ylcarbamate 
• 854022-33-6 C₆₉H₈₃Cl₃N₄O₁₆SSi 
• 854022-31-4 {2-(11-allyloxy-7-hydroxymethyl-2,2,12-trimethyl-4,5,7,10-tetrahydro-1,3,15,17-tetraoxa-6-aza-cyclopenta[a]phenanthren-6-yl)-1-[3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-5-methyl-benzyl]-2-cyano-ethyl}-carbamic acid allyl ester 

Relevant articles and documents

Hafnium trifluoromethanesulfonate (hafnium triflate) as a highly efficient catalyst for chemoselective thioacetalization and transthioacetalization of carbonyl compounds

(Chemical Equation Presented) A range of carbonyl compounds including aliphatic and aromatic aldehydes and ketones were converted to the corresponding thioacetals in high yields in the presence of a catalytic amount of hafnium trifluoromethanesulfonate (0.1 mol %, room temperature). The mild conditions tolerated various sensitive functional and protecting groups and were racemization-free when applied to α-aminoaldehydes. Transacetalization and chemoselective thioacetalization of aromatic aldehydes in the presence of aliphatic aldehydes and ketones were also documented.

Synthetic studies toward ecteinascidin 743

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