854045-95-7

Basic information

• Product Name: Chloro(2-dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl)gold(I), 98%
• Synonyms: Chloro(2-dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl)gold(I), 98%;2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl gold(I) chloride;Chloro[2-dicyclohexyl(2′,6′-dimethoxybiphenyl)phosphine] gold(I);SPhos AuCl
• CAS NO: 854045-95-7
• Molecular Formula: C₂₆H₃₅AuClO₂P
• Molecular Weight: 641.940271
• Mol File: 854045-95-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 263-266°C
• Appearance: white/Powder
• CAS DataBase Reference: Chloro(2-dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl)gold(I), 98%(CAS DataBase Reference)
• NIST Chemistry Reference: Chloro(2-dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl)gold(I), 98%(854045-95-7)
• EPA Substance Registry System: Chloro(2-dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl)gold(I), 98%(854045-95-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 854045-95-7(Hazardous Substances Data)

Usage

Reaction

Highly-efficient and regio-selective catalyst for the selective carbonyl migration in alkynyl-substituted indole-3-carboxamides. Catalyst used in the hydroarylation/aromatization of arene-diynes. Catalyst used in the selective hydration of substituted alkynes at room temperatures.

Upstream product

• 657408-07-6 dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane 
• 29892-37-3 chloro(dimethylsulfide) gold(I) 
• 39929-21-0 (tetrahydrothiophene)gold(I) chloride 

Downstream Products

• 1121960-90-4 2-dicyclohexyl(2′,6′-dimethoxybiphenyl)phosphine gold(I)bis(trifluoromethanesulfonyl)imide 
• 1236160-37-4 [(SPhos)AuNCMe]SbF₆ 
• 1434407-99-4 [dicyclohexyl(2',6'-dimethoxybiphenyl-2-yl)phosphane-κP](prop-1-yn-1-yl)gold 

Relevant articles and documents

Synthesis, Reactivity, and Bonding of Gold(I) Fluorido-Phosphine Complexes

Gold(I) fluorido complexes with phosphine ligands have been synthesized from their respective iodido precursors. The bonding situation in comparison between complexes bearing phosphines and N-heterocyclic carbenes (NHCs) was explored quantum-chemically, obtaining similar results for both. Calculations of the 19F NMR chemical shifts match the experimental values well, including the approximately 40 ppm low-field shifts for the phosphine complexes compared to the NHC complexes, in spite of similar negative charges on fluorine. The reactivity of the highly water-sensitive gold(I) fluorido complexes was studied, resulting in substitution at the metal using trimethylsilyl reagents. The compounds studied were characterized using NMR as well as X-ray diffraction methods.

Gold catalysis: Biarylphosphine ligands as key for the synthesis of dihydroisocoumarins

Agold-catalyzed phenol synthesis was successfully used in the synthesis of dihydroisocoumarins for the first time.Alarge number of gold(I) complexes were prepared and tested; only complexes based on the biarylphosphine motif were successful. CSIRO 2014.