85422-39-5Relevant academic research and scientific papers
1'-methylspiro[indoline-3,4'-piperidine] derivatives: Design, synthesis, molecular docking and anti-tumor activity studies
Li, Junjian,Ye, Lianbao,Wang, Yuanyuan,Liu, Ying,Jin, Xiaobao,Li, Ming
, p. 490 - 498 (2021/10/02)
Background: Spirocyclic indoline compounds widely exist in numerous natural products and synthetic molecules with significant biological activities. In recent years, these kinds of compounds have attracted extensive attention as potent anti-tumor agents i
Novel tetracyclic spiropiperidines. III. 1-Arylspiro[indoline-3,4'-piperidine]s as potential antidepressants
Ong,Profitt,Fortunato,Glamkowski,Ellis,Geyer,Wilker,Burghard
, p. 981 - 986 (2007/10/02)
A series of 1-arylspiro[indoline-3,4'-piperidine]s was synthesized and evaluated for potential antidepressant activity by tetrabenazine (TBZ) ptosis prevention and potentiation of 5-hydroxytryptophan (5-HTP) induced head twitching in pargyline-pretreated
