85429-61-4Relevant articles and documents
Synthesis and Evaluation of Antimicrobial Activity of Some Novel Heterocyclic Compounds from 5-Bromosalicylaldehyde
Abdel-Aziem, Anhar,Baaiu, Basma S.,Abdelhamid, Abdou O.
, p. 3471 - 3480 (2017)
A novel series of coumarins, thiadiazoles, thiazoles, and pyridines were synthesized via reaction of 5-bromosalicylaldehyde with different reagents. Thus, 5-bromosalicylaldehyde 1 was reacted with compounds 2a–d affording iminocoumarins 3a–d, which on hydrolysis with 10% hydrochloric acid, afforded coumarins 4a–d, respectively. On the other hand, reaction of 1 with benzylhydrazinecarbodithioate 5 afforded derivative 6, which reacted with hydrazonoyl halides 7a–f, afforded 1,3,4-thiadiazoles 11a–f, respectively. Moreover, thiazoles 15 and 16 were obtained via reaction of 1 with thiocarbohydrazide 13 and hydrazonoyl halides. However, condensation of 2-acetyl-5-bromobenzofuran 17 with benzaldehyde afforded chalcone 18, which reacted with pyridiniumbromides 19a–c, afforded pyridines 20a–c, respectively. Furthermore, pyridines 21–24 were synthesized from the reaction of chalcone 18 with different active methylene compounds. Reaction of 24 with ethylchloroacetate, chloroacetone, and chloroacetonitrile afforded thienopyridines 26a–c, respectively. The structures of the newly synthesized compounds were established based on their spectral data and elemental analyses. Also, selected newly synthesized compounds were screened for their antimicrobial activity against various microorganisms by disk diffusion method.
The vital role of ditopic: N - N bridging ligands with different lengths in the formation of new binuclear dioxomolybdenum(vi) complexes: Synthesis, crystal structures, supramolecular framework and protein binding studies
Biswal, Debanjana,Roy, Malini,Pramanik, Nikhil Ranjan,Paul, Suvendu,Drew, Michael G. B.,Chakrabarti, Syamal
, p. 16645 - 16664 (2020/10/14)
A new series of binuclear dioxomolybdenum(vi) complexes 1-4 of general formula [(MoO2L)2(N-N)] with an ONS donor Schiff base ligand (H2L = S-benzyl-β-N-(5-bromo-2-hydroxyphenyl)methylenedithiocarbazate) and bridging auxiliary ligands having different leng
Supramolecular frameworks of binuclear dioxomolybdenum(vi) complexes with ONS donor ligands using 4,4′-azopyridine as a pillar: crystal structure, DFT calculations and biological study
Biswal, Debanjana,Pramanik, Nikhil Ranjan,Chakrabarti, Syamal,Drew, Michael G. B.,Mitra, Payel,Acharya, Krishnendu,Biswas, Sujan,Mondal, Tapan Kumar
, p. 8681 - 8694 (2015/11/10)
Three new isostructural pillared binuclear dioxomolybdenum(vi) complexes [(MoO2L1)2(4,4′-azpy)] (1), [(MoO2L2)2(4,4′-azpy)] (2) and [(MoO2L3)2(4,4′-azpy)] (
Inhibition of xanthine oxidase by thiosemicarbazones, hydrazones and dithiocarbazates derived from hydroxy-substituted benzaldehydes
Leigh, Maria,Raines, Daniel J.,Castillo, Carmen E.,Duhme-Klair, Anne K.
experimental part, p. 1107 - 1118 (2012/01/03)
Nonpurine xanthine oxidoreductase (XOR) inhibitors represent important alternatives to the purine analogue allopurinol, which is still the most widely used drug in the treatment of conditions associated with elevated uric acid levels in the blood. By cond
Synthesis, Characterization, Electrochemistry and Oxo-transfer Kinetics of Oxomolybdenum-(VI), -(V) and -(IV) Complexes with ONS Donors
Bhattacharjee, Samiran,Bhattacharyya, Ramgopal
, p. 1357 - 1364 (2007/10/02)
cis-Dioxomolybdenum(VI) complexes of the type are Mo=O...Mo bridged oligomers.In the presence of donors they are converted into monomeric .When a 5-Cl or 5-Br substituent occurs in the salicyl phenyl ring oligomers are not formed, but besides also are obtained.All these complexes undergo oxo transfer to PPh3 at room temperature, furnishing oxomolybdenum(IV) derivatives, , and PPh3O.The complexes in dmf accepts an oxygen atom from Me2SO, affording and Me2S.The ions (2-) (X=Cl or Br) react with the ligands H2L furnishing thiolato-bridged dimers, , which show sub-normal magnetic moments and EPR spectra typical of an antiferromagnetic material.The MoO2(2+) complexes undergo irreversible electrochemical reduction furnishing oxomolybdenum(V) derivatives at potentials commensurate with the nature of substituent in the salicyl group of the ligand.The molybdenum-(V) and -(IV) complexes also show interesting electrochemical reductive as well as oxidative responses centred on the metal.The oxo transfer from (unsubstituted salicyl ring) to PPh3 occurs in a second-order process with rate constant 1.32*10-2 dm3 mol-1 s-1 at 30 deg C.The oxo transfer from Me2SO to the MoO(2+) core is much faster.The reaction between PPh3 and Me2SO furnishing PPh3O and Me2S becomes highly facile in the presence of as catalyst.
Organoxytitanium(IV) and Organotin(IV) Derivatives of Schiff Bases Derived from S-Benzyldithiocarbazate
Pandit, S K,Gopinathan, Sarada,Gopinathan, C
, p. 1004 - 1006 (2007/10/02)
Penta- and hexa-coordinated compounds of titanium(IV) and tin(IV) with schiff bases derived from S-benzyldithiocarbazate and o-hydroxyacetophenone, 5-chlorosalicylaldehyde or 5-bromosalicylaldehyde have been prepared and characterised.
