854306-63-1Relevant academic research and scientific papers
A recyclable catalyst for asymmetric transfer hydrogenation with a formic acid-triethylamine mixture in ionic liquid
Kawasaki, Ikuo,Tsunoda, Kazuya,Tsuji, Tomoko,Yamaguchi, Tomoko,Shibuta, Hiroki,Uchida, Nozomi,Yamashita, Masayuki,Ohta, Shunsaku
, p. 2134 - 2136 (2005)
A novel task-specific ionic ligand with an imidazolium salt moiety was synthesized, and its catalytic ability and recyclability for asymmetric transfer hydrogenation of acetophenone derivatives with a formic acid-triethylamine azeotropic mixture in an ion
Preparation of chiral ligands connected with quaternary ammonium group for recyclable catalytic asymmetric transfer hydrogenation in ionic liquid
Uchimoto, Hitomi,Tsuji, Tomoko,Kawasaki, Ikuo,Arimitsu, Kenji,Yasui, Hiroyuki,Yamashita, Masayuki,Ohta, Shunsaku,Nishide, Kiyoharu
, p. 200 - 209 (2015/03/18)
Reuse of chiral ruthenium catalyst in catalytic asymmetric transfer hydrogenation (CATH) has attracted attention from economic and environmental viewpoints, and reactions using ionic liquids (ILs) as solvent are recognized as one of the most useful methods for reuse of the catalyst. We synthesized (1 S,2 S )- N-( p - toluenesulfonyl)-1,2-diphenylethylenediamine (TsDPEN) derivatives with various ionic moieties, and investigated the effect of their structure with respect to catalytic ability and recyclability in CATH with ILs. Ligand 3a having an imidazolium group showed the best results, and significant differences were observed depending on the structure of the ionic moiety or the length of the alkyl chain connecting the ligand site and the ionic moiety. Among various prochiral ketones used as substrates at various cycles, 3a showed a relatively good result.
