854375-31-8 Usage
Uses
Used in Pharmaceutical Synthesis:
Boc-Dif-Pro-OH is used as a key intermediate in the pharmaceutical industry for the synthesis of various peptide-based drugs. Its unique structure allows for the development of novel drug candidates with enhanced pharmacokinetic properties, potentially leading to more effective treatments for a range of medical conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, Boc-Dif-Pro-OH is utilized as a versatile building block for the design and synthesis of new compounds with potential therapeutic applications. Its difluoro and dimethyl substitutions on the proline ring provide a distinct structural advantage, enabling the creation of innovative drug candidates with improved pharmacological profiles.
Used in Peptide Synthesis:
Boc-Dif-Pro-OH is employed as a valuable component in the synthesis of peptides, which are short chains of amino acids that play a crucial role in various biological processes. (R)-N-tert-butoxycarbonyl-4,4-difluoro-3,3-dimethylproline methyl ester's stability and unique structural features make it an ideal choice for the development of peptide-based therapeutics and diagnostic tools.
Used in Drug Design and Development:
(R)-N-tert-butoxycarbonyl-4,4-difluoro-3,3-dimethylproline methyl ester's unique structure and properties make it an important tool in drug design and development. Boc-Dif-Pro-OH can be used to create new drug candidates with improved pharmacokinetic properties, potentially leading to more effective treatments for various diseases and medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 854375-31-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,4,3,7 and 5 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 854375-31:
(8*8)+(7*5)+(6*4)+(5*3)+(4*7)+(3*5)+(2*3)+(1*1)=188
188 % 10 = 8
So 854375-31-8 is a valid CAS Registry Number.
854375-31-8Relevant academic research and scientific papers
Hu, Shanghui,Martinez, Carlos A.,Kline, Billie,Yazbeck, Daniel,Tao, Junhua,Kucera, David J.
, p. 650 - 654 (2006)
(2S)-4,4-Difluoro-3,3-dimethyl-N-Boc-proline (3) is a key intermediate for the synthesis of HIV protease inhibitors. Here, several approaches for the preparation of enantiopure 3 and its analogues are disclosed. Among these methods, one strategy relies on
METHODS FOR THE PREPARATION OF STEREOISOMERICALLY ENRICHED AMINES
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Page/Page column 41-42, (2008/06/13)
The present invention relates to methods of preparing a stereoisomerically enriched compound of formula (I), wherein R6 is hydrogen, comprising treating a compound of formula (I), wherein R6 is chosen from C1-C10/sub
