854403-01-3Relevant academic research and scientific papers
COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PERIPHERAL NERVE DISORDER
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Paragraph 0250, (2019/10/29)
The present invention provides a means for treating and/or preventing peripheral nerve disorder by facilitating regeneration of peripheral nerves. Specifically, the present invention provides a composition for treating and/or preventing peripheral nerve d
Lissencephaly therapeutic agent
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, (2016/07/27)
An object of the present invention is to provide a medicament and method for treating lissencephaly patients. The present invention provides a lissencephaly therapeutic or preventive agent comprising a compound represented by the general formula (I): wher
LISSENCEPHALY THERAPEUTIC AGENT
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, (2013/10/22)
An object of the present invention is to provide a medicament and method for treating lissencephaly patients. The present invention provides a lissencephaly therapeutic or preventive agent comprising a compound represented by the general formula (I): wher
ALPHA-KETOAMIDE DERIVATIVE, AND PRODUCTION METHOD AND USE THEREOF
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Page/Page column 50-51, (2008/06/13)
The present invention provides a compound represented by the formula (I): (INSERT CHEMICAL FORMULA) (wherein R1 is a lower alkyl substituted by a lower alkoxy or a heterocyclic group, or a heterocyclic group; R2 is a lower alkyl opti
Exploration of orally available calpain inhibitors: Peptidyl α-ketoamides containing an amphiphile at P3 site
Shirasaki, Yoshihisa,Miyashita, Hiroyuki,Yamaguchi, Masazumi,Inoue, Jun,Nakamura, Masayuki
, p. 4473 - 4484 (2007/10/03)
A novel series of dipeptidyl α-ketoamide derivatives with amphiphile was designed and synthesized as water-soluble calpain inhibitors. The introduction of amphiphiles at the P3 site increased water solubility without loss of membrane permeability and prov
