854601-60-8 Usage
Uses
Used in Bioconjugation:
3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine is used as a PEG linker for bioconjugation applications. The reactive amino group allows for the attachment of various biomolecules, such as peptides, proteins, and nucleic acids, to create stable and functional bioconjugates.
Used in Drug Delivery Systems:
In the pharmaceutical industry, 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine is used as a PEG linker for drug delivery systems. The hydrophilic PEG spacer enhances the solubility and stability of drug molecules, improving their pharmacokinetic properties and therapeutic efficacy.
Used in Diagnostics:
In the medical diagnostics field, 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine is used as a PEG linker for the development of diagnostic agents. The PEG spacer can be used to attach imaging agents or targeting moieties to biomolecules, enhancing their performance in diagnostic assays and imaging techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 854601-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,4,6,0 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 854601-60:
(8*8)+(7*5)+(6*4)+(5*6)+(4*0)+(3*1)+(2*6)+(1*0)=168
168 % 10 = 8
So 854601-60-8 is a valid CAS Registry Number.
854601-60-8Relevant academic research and scientific papers
Lutz, Eric,Moulin, Emilie,Tchakalova, Vera,Benczédi, Daniel,Herrmann, Andreas,Giuseppone, Nicolas
, p. 13457 - 13467 (2021)
Despite their intrinsic hydrolysable character, imine bonds can become remarkably stable in water when self-assembled in amphiphilic micellar structures. In this work, we systematically studied some of these structures and the influence of various parameters that can be used to take control of their hydrolysis, including pH, concentration, the position of the imine function in the amphiphilic structure, relative lengths of the linked hydrophilic and hydrophobic moieties. Thermodynamic and kinetic data led us to the rational design of stable imines in water, partly based on the location of the imine function within the hydrophobic part of the amphiphile and on a predictable quantitative term that we define as the total hydrophilic–lipophilic balance (HLB). In addition, we show that such stable systems are also stimuli-responsive and therefore, of potential interest in trapping and releasing micellar components on demand.
