854601-80-2

Basic information

• Product Name: m-PEG5-bromide
• Synonyms: m-PEG5-bromide;Methyl-PEG5-bromide;Bromo-PEG5-methoxy;mPEG5-Br
• CAS NO: 854601-80-2
• Molecular Formula: C₁₁H₂₃BrO₅
• Molecular Weight: 315.20132
• Mol File: 854601-80-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 342.4±32.0 °C(Predicted)
• Appearance: /
• Density: 1.235±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: m-PEG5-bromide(CAS DataBase Reference)
• NIST Chemistry Reference: m-PEG5-bromide(854601-80-2)
• EPA Substance Registry System: m-PEG5-bromide(854601-80-2)

Safety Data

• Hazardous Substances Data: 854601-80-2(Hazardous Substances Data)

Usage

Description

m-PEG5-bromide is a PEG linker containing a bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

Upstream product

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Downstream Products

• 854601-76-6 mPEG₅-hydroxyzine 
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Relevant articles and documents

Engineering Nanoparticulate Organic Photocatalysts via a Scalable Flash Nanoprecipitation Process for Efficient Hydrogen Production

Directly converting sunlight into hydrogen fuels using particulate photocatalysts represents a sustainable route for clean energy supply. Organic semiconductors have emerged as attractive candidates but always suffer from optical and exciton recombination losses with large exciton “dead zone” inside the bulk material, severely limiting the catalytic performance. Herein, we demonstrate a facile strategy that combines a scalable flash nanoprecipitation (FNP) method with hydrophilic soluble polymers (PC-PEG5 and PS-PEG5) to prepare highly efficient nanosized photocatalysts without using surfactants. Significantly, a 70-fold enhancement of hydrogen evolution rate (HER) is achieved for nanosized PC-PEG5, and the FNP-processed PS-PEG5 shows a peak HER rate of up to 37.2 mmol h?1 g?1 under full-spectrum sunlight irradiation, which is among the highest results for polymer photocatalysts. A scaling-up production of nanocatalyst is demonstrated with the continuously operational FNP.

Chemically modified small molecules

The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer obtained from a monodisperse or bimodal water-soluble oligomer composition. A conjugate of the invention, when administered by any of a number of administration routes, exhibits a reduced biological membrane crossing rate as compared to the biological membrane crossing rate of the small molecule drug not attached to the water-soluble oligomer.