854613-07-3

Upstream product

• 162971-56-4 (R)-4-<(tert-butyldiphenylsilyl)oxy>pentan-1-ol 
• 162971-57-5 (+)-(R)-1-iodo-4-(t-butyldiphenylsilyloxy)-pentane 
• 854612-93-4 methyl (2E,7R)-7-(t-butyldiphenylsilyloxy)-2-hydroxymethyl-2-octenoate 
• 854612-92-3 methyl (2Z,7R)-2-bromomethyl-7-(t-butyldiphenylsilyloxy)-2-octenoate 
• 854612-91-2 methyl (3RS,7R)-7-(t-butyldiphenylsilyloxy)-3-hydroxy-2-methyleneoctanoate 
• 854612-89-8 ethyl (2E,4R)-4-(t-butyldiphenylsilyloxy)-2-pentenoate 
• 854612-90-1 (5R)-5-(t-butyldiphenylsilyloxy)hexanenitrile 
• 855256-87-0 (5R)-5-[1-(tert-butyl)-1,1-diphenylsilyl]oxyhexanal 
• 561038-05-9 (R)-2-(tert-butyldiphenylsilanyloxy)propionic acid methyl ester 
• 854612-98-9 (2S,3R,4E,9R)-4-(t-butyldimethylsilyloxy)methyl-9-(t-butyldiphenylsilyloxy)-3-methoxymethoxy-2-methyldec-4-en-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 167468-64-6 (2R)-2-(tert-butyldiphenylsiloxy)propanal 
• 854612-97-8 (4R)-4-benzyl-3-[(2R,3R,4E,9R)-4-(t-butyldimethylsilyloxy)methyl-9-(t-butyldiphenylsilyloxy)-3-methoxymethoxy-2-methyldec-4-enoyl]oxazolidin-2-one 
• 854612-94-5 methyl (2E,7R)-2-(t-butyldimethylsilyloxy)methyl-7-(t-butyldiphenylsilyloxy)-2-octenoate 

Downstream Products

• 854612-99-0 (3S,4R,5E,10R)-1,1-dibromo-5-(t-butyldimethylsilyloxy)methyl-10-(t-butyldiphenylsilyloxy)-4-methoxymethoxy-3-methylundeca-1,5-diene 
• 854613-01-7 (3S,4R,5Z,10R)-1-bromo-10-(t-butyldiphenylsilyloxy)-5-methoxycarbonyl-4-methoxymethoxy-3-methylundec-5-en-1-yne 
• 854613-00-6 (3S,4R,5E,10R)-1-bromo-10-(t-butyldiphenylsilyloxy)-5-hydroxymethyl-4-methoxymethoxy-3-methylundec-5-en-1-yne 

Relevant academic research and scientific papers

Total synthesis of (+)-tubelactomicin A. 2. Synthesis of the upper-half segment and completion of the total synthesis

(Chemical Equation Presented) We have completed the total synthesis of natural (+)-tubelactomicin A (1), a 16-membered macrolide antibiotic. This Letter presents a highly efficient synthesis of the upper-half segment (C14-C24) and the completion of the to