854626-60-1

Basic information

• Product Name: 4-p-tolyloxymethyl-benzonitrile
• Synonyms: 4-p-tolyloxymethyl-benzonitrile
• CAS NO: 854626-60-1
• Molecular Weight: 223.274
• Mol File: 854626-60-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-p-tolyloxymethyl-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-p-tolyloxymethyl-benzonitrile(854626-60-1)
• EPA Substance Registry System: 4-p-tolyloxymethyl-benzonitrile(854626-60-1)

Safety Data

• Hazardous Substances Data: 854626-60-1(Hazardous Substances Data)

Upstream product

• 1121-70-6 sodium 4-methylphenoxide 
• 17201-43-3 4-cyanobenzyl bromide 
• 5720-05-8 4-methylphenylboronic acid 

Downstream Products

• 854627-20-6 4-p-tolyloxymethyl-benzoyl chloride 
• 88382-46-1 4-((4-methylphenoxy)methyl)benzoic acid 

Relevant articles and documents

Pd(OAc)2-catalyzed synthesis of benzyl phenyl ether derivatives with H2O2 as an oxidant in neat water

A new protocol for Pd(OAc)2-catalyzed reactions of different benzyl bromides and various arylboronic acids has been developed to form functionalized benzyl phenyl ethers. This method represents the first instance where arylboronic acid is used as a reaction substrate for benzyl phenyl ether synthesis with H2O2 as the green oxidant under atmospheric oxygen and pure H2O as an environmental friendly solvent without the requirement for phosphine- and N-based ligands, remarkable functional group tolerance, and considerable yield.