854650-81-0

Basic information

• Product Name: N,N'-bis-(4-bromo-phenyl)-propanediyldiamine
• Synonyms: N,N'-bis-(4-bromo-phenyl)-propanediyldiamine
• CAS NO: 854650-81-0
• Molecular Weight: 384.113
• Mol File: 854650-81-0.mol

Chemical Properties

• CAS DataBase Reference: N,N'-bis-(4-bromo-phenyl)-propanediyldiamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-bis-(4-bromo-phenyl)-propanediyldiamine(854650-81-0)
• EPA Substance Registry System: N,N'-bis-(4-bromo-phenyl)-propanediyldiamine(854650-81-0)

Safety Data

• Hazardous Substances Data: 854650-81-0(Hazardous Substances Data)

Upstream product

• 109-64-8 1,3-dibromo-propane 
• 106-40-1 4-bromo-aniline 
• 30881-03-9 N,N'-bis-(4-bromophenyl)formamidine 

Relevant articles and documents

Catalyst-Free Synthesis of Aryl Diamines via a Three-Step Reaction Process

The formation of C-N bonds with aryl amines is one of the most widely studied reactions in organic chemistry. Despite this, it is still highly challenging, often requiring expensive, precious metal-based catalysts. Here we report an easy catalyst-free methodology for constructing C-N bonds. The method, which proceeds via the in situ formation of closed ring amidinium ions, allows the preparation of a series of symmetrical and/or unsymmetrical aryl diamines in notably high yields (82-98%) and purity and with a variety of different substituents. The methodology is shown successful for the preparation of aryl diamines having para- and/or meta-substituted carboxyl, nitro, bromo, methoxy, or methyl groups. This green synthetic pathway, which is catalyst free, requires only three steps, and proceeds without the need for purification. Further, it is a new sustainable, economically viable method to achieve an otherwise challenging bond formation.