854753-94-9

Upstream product

• 854753-93-8 {1-[5-oxo-4-(4-pyridin-2-ylbenzyl)tetrahydrofuran-2-yl]-2-phenylethyl}carbamic acid tert-butyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 854753-97-2 benzyl (2R,4S,5S)-5-(tert-butoxycarbonyl)amino-4-hydroxy-6-phenyl-1-(4-(pyridin-2-yl)phenyl)hexan-2-ylcarbamate 
• 854753-96-1 benzyl (2S,4S,5S)-5-(tert-butoxycarbonyl)amino-4-hydroxy-6-phenyl-1-(4-(pyridin-2-yl)phenyl)hexan-2-ylcarbamate 

Relevant academic research and scientific papers

An efficient, stereoselective synthesis of the hydroxyethylene dipeptide isostere core for the HIV protease inhibitor A-792611

A stereoselective synthesis of the hydroxyethylene dipeptide isostere 1 is described. The route employs a substrate-directed kinetic protonation of an α/γ-substituted lactone to afford the desired stereochemistry. A method for converting the diastereomeri

HIV protease inhibiting compounds

A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.