85486-86-8

Upstream product

• 80829-71-6 (R)-3-((S)-1-Acetoxy-ethyl)-1-(2,4-dimethoxy-benzyl)-4-oxo-azetidine-2,2-dicarboxylic acid diethyl ester 
• 81902-52-5 (+/-)-<3S-<3α(S^*),4α>>-1-(2,4-dimethoxybenzyl)-3-(1-acetoxyethyl)-4-ethoxycarbonyl-2-azetidinone-4-carboxylic acid 
• 85486-82-4 (+/-)-<1α,4α,5α>-7-(2,4-dimethoxybenzyl)-2,6-dioxo-4-methyl-3-oxa-7-azabicyclo<3.2.0>heptane-1-carboxylic acid 
• 85486-81-3 (+/-)-(R^*,S^*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid) 

Downstream Products

• 81902-53-6 (+/-)-<1α,4α,5α>-7-(2,4-dimethoxybenzyl)-2,6-dioxo-4-methyl-3-oxa-7-azabicyclo<3.2.0>heptane 

Relevant academic research and scientific papers

STEREOSPECIFIC SYNTHESIS OF RACEMIC INTERMEDIATES OF THE PENEMS AND THE CARBAPENEMS FROM TRANS-CROTONIC ACID

Stereocontrolled syntheses of two (+)-3-(1-t-butyldimethylsilyloxyethyl)-4-acetoxy-2-azetidinones (cis-10 and trans-10), which are key intermediates for the penems and the carbapenems, from trans-crotonic acid are reported.