85486-81-3

Upstream product

• 81902-52-5 (+/-)-<3S-<3α(S^*),4α>>-1-(2,4-dimethoxybenzyl)-3-(1-acetoxyethyl)-4-ethoxycarbonyl-2-azetidinone-4-carboxylic acid 
• 80829-71-6 (R)-3-((S)-1-Acetoxy-ethyl)-1-(2,4-dimethoxy-benzyl)-4-oxo-azetidine-2,2-dicarboxylic acid diethyl ester 

Downstream Products

• 85486-82-4 (+/-)-<1α,4α,5α>-7-(2,4-dimethoxybenzyl)-2,6-dioxo-4-methyl-3-oxa-7-azabicyclo<3.2.0>heptane-1-carboxylic acid 
• 81902-66-1 (+/-)-<1α,4α,5α>-t-butyl-7-(2,4-dimethoxybenzyl)-2,6-dioxo-4-methyl-3-oxa-7-azabicyclo<3.2.0>heptane-1-carboxylate 
• 85486-88-0 (+/-)-<3α(S^*),4β>-t-butyl-1-(2,4-dimethoxybenzyl)-3-(1-t-butoxycarbonylcarboxyethyl)-2-azetidinone-4-carboxylate 
• 85486-88-0 (+/-)-<3α(S^*),4α>-t-butyl-1-(2,4-dimethoxybenzyl)-3-(1-t-butoxycarbonylcarboxyethyl)-2-azetidinone-4-carboxylate 
• 85486-84-6 (+/-)-<1α,2α,4α,5α>-7-(2,4-dimethoxybenzyl)-2-hydroxy-4-methyl-3-oxa-6-oxo-7-azabicyclo<3.2.0>heptane 
• 85486-85-7 (+/-)-<1α,4α,5α>-7-(2,4-dimethoxybenzyl)-2,6-dioxo-3-oxa-4-methyl-7-azabicyclo<3.2.0>heptane-1-carboxylic acid chloride 
• 85486-83-5 (1S,2R,5R)-6-(2,4-Dimethoxy-benzyl)-4-hydroxy-2-methyl-7-oxo-3-oxa-6-aza-bicyclo[3.2.0]heptane-5-carboxylic acid methyl ester 
• 85508-71-0 (+/-)-<1α,4α,5α>-methyl-7-(2,4-dimethoxybenzyl)-2,6-dioxo-4-methyl-3-oxa-7-azabicyclo<3.2.0>heptane-1-carboxylate 
• 85486-86-8 (1S,2R,5R)-6-(2,4-Dimethoxy-benzyl)-2-methyl-4,7-dioxo-3-oxa-6-aza-bicyclo[3.2.0]heptane-5-carboperoxoic acid tert-butyl ester 
• 81902-53-6 (+/-)-<1α,4α,5α>-7-(2,4-dimethoxybenzyl)-2,6-dioxo-4-methyl-3-oxa-7-azabicyclo<3.2.0>heptane 
• 87325-87-9 (+/-)-<3α(S^*),4β>-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-4-methoxycarbonyl-4-hydroxymethyl-2-azetidinone 
• 87325-89-1 (1S,2R,5R)-4-Acetoxy-6-(2,4-dimethoxy-benzyl)-2-methyl-7-oxo-3-oxa-6-aza-bicyclo[3.2.0]heptane-5-carboxylic acid methyl ester 
• 87325-88-0 (+/-)-<3α(S^*),4β>-1-(2,4-dimethoxybenzyl)-3-(1-acetoxyethyl)-4-methoxycarbonyl-4-acetoxymethyl-2-azetidinone 
• 81902-54-7 (2S,3S)-1-(2,4-Dimethoxy-benzyl)-3-((R)-1-hydroxy-ethyl)-4-oxo-azetidine-2-carboxylic acid 

Relevant academic research and scientific papers

STEREOSPECIFIC SYNTHESIS OF RACEMIC INTERMEDIATES OF THE PENEMS AND THE CARBAPENEMS FROM TRANS-CROTONIC ACID

Stereocontrolled syntheses of two (+)-3-(1-t-butyldimethylsilyloxyethyl)-4-acetoxy-2-azetidinones (cis-10 and trans-10), which are key intermediates for the penems and the carbapenems, from trans-crotonic acid are reported.